Cargando…

The reduction of DSS-induced colitis severity in mice exposed to cigarette smoke is linked to immune modulation and microbial shifts

Exposure to cigarette smoke (CS) causes detrimental health effects, increasing the risk of cardiovascular, pulmonary diseases and carcinogenesis in exposed individuals. The impact of CS on Inflammatory Bowel Disease (IBD) has been established by a number of epidemiological and clinical studies. In f...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lo Sasso, Giuseppe, Phillips, Blaine W., Sewer, Alain, Battey, James N. D., Kondylis, Athanasios, Talikka, Marja, Titz, Bjoern, Guedj, Emmanuel, Peric, Dariusz, Bornand, David, Dulize, Remi, Merg, Celine, Corciulo, Maica, Ouadi, Sonia, Yanuar, Rendy, Tung, Ching Keong, Ivanov, Nikolai V., Peitsch, Manuel C., Hoeng, Julia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7052152/ https://www.ncbi.nlm.nih.gov/pubmed/32123204 http://dx.doi.org/10.1038/s41598-020-60175-3

Ejemplares similares

Anatabine ameliorates intestinal inflammation and reduces the production of pro-inflammatory factors in a dextran sulfate sodium mouse model of colitis
por: Ruiz Castro, Pedro A., et al.
Publicado: (2020)

Tobacco Alkaloid Assessment in a DSS-Induced Colitis Mouse Model with a Fully Humanized Immune System
por: Verhaeghe, Catherine, et al.
Publicado: (2023)

A meta-analysis of microRNAs expressed in human aerodigestive epithelial cultures and their role as potential biomarkers of exposure response to nicotine-containing products
por: Sewer, Alain, et al.
Publicado: (2020)

Discriminating Spontaneous From Cigarette Smoke and THS 2.2 Aerosol Exposure-Related Proliferative Lung Lesions in A/J Mice by Using Gene Expression and Mutation Spectrum Data
por: Xiang, Yang, et al.
Publicado: (2021)

Systems biology reveals anatabine to be an NRF2 activator
por: Messinis, Dimitris E., et al.
Publicado: (2022)

Quantification of biological network perturbations for mechanistic insight and diagnostics using two-layer causal models
por: Martin, Florian, et al.
Publicado: (2014)

A 6-month inhalation toxicology study in Apoe(−/−) mice demonstrates substantially lower effects of e-vapor aerosol compared with cigarette smoke in the respiratory tract
por: Wong, Ee Tsin, et al.
Publicado: (2021)

Comprehensive systems biology analysis of a 7-month cigarette smoke inhalation study in C57BL/6 mice
por: Ansari, Sam, et al.
Publicado: (2016)

Construction of a Suite of Computable Biological Network Models Focused on Mucociliary Clearance in the Respiratory Tract
por: Yepiskoposyan, Hasmik, et al.
Publicado: (2019)

Systems toxicology study reveals reduced impact of heated tobacco product aerosol extract relative to cigarette smoke on premature aging and exacerbation effects in aged aortic cells in vitro
por: Poussin, Carine, et al.
Publicado: (2021)

Nicotine-mediated effects in neuronal and mouse models of synucleinopathy
por: Fares, Mohamed Bilal, et al.
Publicado: (2023)

Mechanistic Evaluation of the Impact of Smoking and Chronic Obstructive Pulmonary Disease on the Nasal Epithelium
por: Talikka, Marja, et al.
Publicado: (2017)

Multi-omics systems toxicology study of mouse lung assessing the effects of aerosols from two heat-not-burn tobacco products and cigarette smoke
por: Titz, Bjoern, et al.
Publicado: (2020)

Semi-Automated Curation Allows Causal Network Model Building for the Quantification of Age-Dependent Plaque Progression in ApoE(−/−) Mouse
por: Szostak, Justyna, et al.
Publicado: (2016)

NPA: an R package for computing network perturbation amplitudes using gene expression data and two-layer networks
por: Martin, Florian, et al.
Publicado: (2019)

An 8-Month Systems Toxicology Inhalation/Cessation Study in Apoe(−/−) Mice to Investigate Cardiovascular and Respiratory Exposure Effects of a Candidate Modified Risk Tobacco Product, THS 2.2, Compared With Conventional Cigarettes
por: Phillips, Blaine, et al.
Publicado: (2016)

An 8-Month Systems Toxicology Inhalation/Cessation Study in Apoe(−/−) Mice to Investigate Cardiovascular and Respiratory Exposure Effects of a Candidate Modified Risk Tobacco Product, THS 2.2, Compared With Conventional Cigarettes
por: Phillips, Blaine, et al.
Publicado: (2016)

Systems toxicology approaches enable mechanistic comparison of spontaneous and cigarette smoke-related lung tumor development in the A/J mouse model
por: Luettich, Karsta, et al.
Publicado: (2014)

Evaluation of toxicity of aerosols from flavored e-liquids in Sprague–Dawley rats in a 90-day OECD inhalation study, complemented by transcriptomics analysis
por: Ho, Jenny, et al.
Publicado: (2020)

Systems toxicology assessment of a representative e-liquid formulation using human primary bronchial epithelial cells
por: Marescotti, Diego, et al.
Publicado: (2019)

A Meta-Analysis of the Performance of a Blood-Based Exposure Response Gene Signature Across Clinical Studies on the Tobacco Heating System 2.2 (THS 2.2)
por: Martin, Florian, et al.
Publicado: (2019)

Proteomics and Lipidomics in Inflammatory Bowel Disease Research: From Mechanistic Insights to Biomarker Identification
por: Titz, Bjoern, et al.
Publicado: (2018)

Effects of Cigarette Smoke, Cessation, and Switching to Two Heat-Not-Burn Tobacco Products on Lung Lipid Metabolism in C57BL/6 and Apoe(−/−) Mice—An Integrative Systems Toxicology Analysis
por: Titz, Bjoern, et al.
Publicado: (2016)

Transcriptional profiling and targeted proteomics reveals common molecular changes associated with cigarette smoke-induced lung emphysema development in five susceptible mouse strains
por: Cabanski, Maciej, et al.
Publicado: (2015)

Respiratory Effects of Exposure to Aerosol From the Candidate Modified-Risk Tobacco Product THS 2.2 in an 18-Month Systems Toxicology Study With A/J Mice
por: Titz, Bjoern, et al.
Publicado: (2020)

Effects of cigarette smoke exposure on a mouse model of multiple sclerosis
por: Ho, Jenny, et al.
Publicado: (2022)

In vitro systems toxicology approach to investigate the effects of repeated cigarette smoke exposure on human buccal and gingival organotypic epithelial tissue cultures
por: Schlage, Walter K., et al.
Publicado: (2014)

Assessment of inhalation toxicity of cigarette smoke and aerosols from flavor mixtures: 5‐week study in A/J mice
por: Wong, Ee Tsin, et al.
Publicado: (2022)

Impact Assessment of Cigarette Smoke Exposure on Organotypic Bronchial Epithelial Tissue Cultures: A Comparison of Mono-Culture and Coculture Model Containing Fibroblasts
por: Iskandar, Anita R., et al.
Publicado: (2015)

Comparative effects of a candidate modified-risk tobacco product Aerosol and cigarette smoke on human organotypic small airway cultures: a systems toxicology approach
por: Iskandar, Anita R., et al.
Publicado: (2017)

Impact of 6-Month Exposure to Aerosols From Potential Modified Risk Tobacco Products Relative to Cigarette Smoke on the Rodent Gastrointestinal Tract
por: Battey, James N. D., et al.
Publicado: (2021)

Causal Biological Network Model for Inflammasome Signaling Applied for Interpreting Transcriptomic Changes in Various Inflammatory States
por: Yepiskoposyan, Hasmik, et al.
Publicado: (2022)

Impact Assessment of Repeated Exposure of Organotypic 3D Bronchial and Nasal Tissue Culture Models to Whole Cigarette Smoke
por: Kuehn, Diana, et al.
Publicado: (2015)

Causal biological network database: a comprehensive platform of causal biological network models focused on the pulmonary and vascular systems
por: Boué, Stéphanie, et al.
Publicado: (2015)

Systems Approaches Evaluating the Perturbation of Xenobiotic Metabolism in Response to Cigarette Smoke Exposure in Nasal and Bronchial Tissues
por: Iskandar, Anita R., et al.
Publicado: (2013)

Systems Toxicology Approach for Assessing Developmental Neurotoxicity in Larval Zebrafish
por: Li, Roman A., et al.
Publicado: (2021)

Apical Medium Flow Influences the Morphology and Physiology of Human Proximal Tubular Cells in a Microphysiological System
por: Specioso, Gabriele, et al.
Publicado: (2022)

Proteomics for systems toxicology
por: Titz, Bjoern, et al.
Publicado: (2014)

Systems biology approach highlights mechanistic differences between Crohn’s disease and ulcerative colitis
por: Ruiz Castro, Pedro A., et al.
Publicado: (2021)

The species translation challenge—A systems biology perspective on human and rat bronchial epithelial cells
por: Poussin, Carine, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_2jt8rish1onkc5ve37cq4g0lso