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Chlorzoxazone, a small molecule drug, augments immunosuppressive capacity of mesenchymal stem cells via modulation of FOXO3 phosphorylation

Nowadays, immune diseases are a large burden in healthcare. Mesenchymal stem cells (MSCs) have prominent ability in immunomodulation and have been applicated on treating many immune-related diseases. However, the clinical outcomes can be disparate and sometimes completely counterproductive beyond ex...

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Detalles Bibliográficos
Autores principales: Deng, Luchan, Li, Hongling, Su, Xiaodong, Zhang, Yingjie, Xu, Haoying, Fan, Linyuan, Fan, Junfen, Han, Qin, Bai, Xueyuan, Zhao, Robert Chunhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7052156/
https://www.ncbi.nlm.nih.gov/pubmed/32123161
http://dx.doi.org/10.1038/s41419-020-2357-8