Basic Hallmarks of Urothelial Cancer Unleashed in Primary Uroepithelium by Interference with the Epigenetic Master Regulator ODC1

Urothelial carcinoma (UC) is a common disease causing significant morbidity and mortality as well as considerable costs for health systems. Extensive aberrant methylation of DNA is broadly documented in early UC, contributing to genetic instability, altered gene expression and tumor progression. How...

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Detalles Bibliográficos
Autores principales: Erichsen, Lars, Seifert, Hans-Helge, Schulz, Wolfgang A., Hoffmann, Michèle J., Niegisch, Günter, Araúzo-Bravo, Marcos J., Bendhack, Marcelo L., Poyet, Cedric, Hermanns, Thomas, Beermann, Agnes, Hassan, Mohamed, Theis, Lisa, Mahmood, Wardah, Santourlidis, Simeon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7052216/
https://www.ncbi.nlm.nih.gov/pubmed/32123240
http://dx.doi.org/10.1038/s41598-020-60796-8

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