A bacterial cell factory converting glucose into scyllo-inositol, a therapeutic agent for Alzheimer’s disease

A rare stereoisomer of inositol, scyllo-inositol, is a therapeutic agent that has shown potential efficacy in preventing Alzheimer’s disease. Mycobacterium tuberculosis ino1 encoding myo-inositol-1-phosphate (MI1P) synthase (MI1PS) was introduced into Bacillus subtilis to convert glucose-6-phosphate...

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Detalles Bibliográficos
Autores principales: Michon, Christophe, Kang, Choong-Min, Karpenko, Sophia, Tanaka, Kosei, Ishikawa, Shu, Yoshida, Ken-ichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7052218/
https://www.ncbi.nlm.nih.gov/pubmed/32123276
http://dx.doi.org/10.1038/s42003-020-0814-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7052218/
https://www.ncbi.nlm.nih.gov/pubmed/32123276
http://dx.doi.org/10.1038/s42003-020-0814-7

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