MFN1-dependent alteration of mitochondrial dynamics drives hepatocellular carcinoma metastasis by glucose metabolic reprogramming

BACKGROUND: Mitochondrial dynamics plays an important role in tumour progression. However, how these dynamics integrate tumour metabolism in hepatocellular carcinoma (HCC) metastasis is still unclear. METHODS: The mitochondrial fusion protein mitofusin-1 (MFN1) expression and its prognostic value ar...

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Detalles Bibliográficos
Autores principales: Zhang, Ze, Li, Tian-En, Chen, Mo, Xu, Da, Zhu, Ying, Hu, Bei-Yuan, Lin, Zhi-Fei, Pan, Jun-Jie, Wang, Xuan, Wu, Chao, Zheng, Yan, Lu, Lu, Jia, Hu-Liang, Gao, Song, Dong, Qiong-Zhu, Qin, Lun-Xiu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7052272/
https://www.ncbi.nlm.nih.gov/pubmed/31819189
http://dx.doi.org/10.1038/s41416-019-0658-4

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