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Aggregation of Human Mesenchymal Stromal Cells Eliminates Their Ability to Suppress Human T Cells

Mesenchymal stromal cells (MSCs) are administered locally to treat sites of inflammation. Local delivery is known to cause MSCs to aggregate into “spheroids,” which alters gene expression and phenotype. While adherent MSCs are highly efficient in their inhibition of T cells, whether or not this prop...

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Detalles Bibliográficos
Autores principales:	Burand, Anthony J., Di, Lin, Boland, Lauren K., Boyt, Devlin T., Schrodt, Michael V., Santillan, Donna A., Ankrum, James A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7052295/ https://www.ncbi.nlm.nih.gov/pubmed/32158443 http://dx.doi.org/10.3389/fimmu.2020.00143

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