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A Pilot Study of Baseline Spatial Genomic Heterogeneity in Primary Gastric Cancers Using Multi-Region Endoscopic Sampling

Intertumoral heterogeneity among actionable biomarkers including ERBB2, FGFR2 and EGFR has been observed to occur under therapeutic pressure in advanced gastric cancer. However, baseline intratumoral heterogeneity at diagnosis is understudied and may impact clinical outcomes. We sought to explore in...

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Detalles Bibliográficos
Autores principales:	Chao, Joseph, Lee, Jeeyun, Kim, Kyung, Kang, So Young, Lee, Taehyang, Kim, Kyoung-Mee, Kim, Seung Tae, Klempner, Samuel J., Lee, Hyuk
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7052337/ https://www.ncbi.nlm.nih.gov/pubmed/32158697 http://dx.doi.org/10.3389/fonc.2020.00225

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