Adjuvant Screen Identifies Synthetic DNA-Encoding Flt3L and CD80 Immunotherapeutics as Candidates for Enhancing Anti-tumor T Cell Responses

Overcoming tolerance to tumor-associated antigens remains a hurdle for cancer vaccine-based immunotherapy. A strategy to enhance the anti-tumor immune response is the inclusion of adjuvants to cancer vaccine protocols. In this report, we generated and systematically screened over twenty gene-based m...

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Detalles Bibliográficos
Autores principales: Thorne, Amy Haseley, Malo, Kirsten N., Wong, Ashley J., Nguyen, Tricia T., Cooch, Neil, Reed, Charles, Yan, Jian, Broderick, Kate E., Smith, Trevor R. F., Masteller, Emma L., Humeau, Laurent
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7052369/
https://www.ncbi.nlm.nih.gov/pubmed/32161596
http://dx.doi.org/10.3389/fimmu.2020.00327

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7052369/
https://www.ncbi.nlm.nih.gov/pubmed/32161596
http://dx.doi.org/10.3389/fimmu.2020.00327

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