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NK Cell Function Regulation by TGF-β-Induced Epigenetic Mechanisms
TGF-β is a potent immunosuppressive cytokine that severely affects the function of NK cells. Tumor cells can take advantage of this ability, enriching their surrounding microenvironment with TGF-β. TGF-β can alter the expression of effector molecules and of activating and chemokine receptors, influe...
Autores principales: | Regis, Stefano, Dondero, Alessandra, Caliendo, Fabio, Bottino, Cristina, Castriconi, Roberta |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7052483/ https://www.ncbi.nlm.nih.gov/pubmed/32161594 http://dx.doi.org/10.3389/fimmu.2020.00311 |
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