How polypharmacologic is each chemogenomics library?

AIM: High-throughput phenotypic screens have emerged as a promising avenue for small-molecule drug discovery. The challenge faced in high-throughput phenotypic screens is target deconvolution once a small molecule hit is identified. Chemogenomics libraries have emerged as an important tool for meeti...

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Detalles Bibliográficos
Autores principales: Ni, Eric, Kwon, Eehjoe, Young, Lauren M., Felsovalyi, Klara, Fuller, Jennifer, Cardozo, Timothy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Newlands Press Ltd 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7052528/
https://www.ncbi.nlm.nih.gov/pubmed/32149277
http://dx.doi.org/10.4155/fdd-2019-0032

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7052528/
https://www.ncbi.nlm.nih.gov/pubmed/32149277
http://dx.doi.org/10.4155/fdd-2019-0032

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