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Effectiveness of surgical resection for complicated liver cancer and its influencing factors: A retrospective study

BACKGROUND: Surgical resection is the preferred method for patients with complex liver cancer. But the tumor is in a special position, the surgery is highly risky, postoperative complications can easily occur, and the prognosis is not ideal. AIM: To investigate the effectiveness of surgical resectio...

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Autores principales: Yu, Jian, Wu, Zhi-Zheng, Li, Teng, Xu, Ying, Zhao, Yu-Cheng, Zhang, Bo-Lun, Tian, Hu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7052557/
https://www.ncbi.nlm.nih.gov/pubmed/32149057
http://dx.doi.org/10.12998/wjcc.v8.i4.736
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author Yu, Jian
Wu, Zhi-Zheng
Li, Teng
Xu, Ying
Zhao, Yu-Cheng
Zhang, Bo-Lun
Tian, Hu
author_facet Yu, Jian
Wu, Zhi-Zheng
Li, Teng
Xu, Ying
Zhao, Yu-Cheng
Zhang, Bo-Lun
Tian, Hu
author_sort Yu, Jian
collection PubMed
description BACKGROUND: Surgical resection is the preferred method for patients with complex liver cancer. But the tumor is in a special position, the surgery is highly risky, postoperative complications can easily occur, and the prognosis is not ideal. AIM: To investigate the effectiveness of surgical resection for complex liver cancer and its influencing factors. METHODS: Fifty-seven patients who had complicated liver cancer and underwent surgical resection at our hospital from August 2015 to August 2016 were enrolled in this study. All patients were followed for three years, and their postoperative complications, survival, and factors that impacted their survival were analyzed. RESULTS: The total incidence of postoperative complications was 45.61%, and the incidence of pleural effusion was the highest at 28.07%. There were no correlations between the 2-year and 3-year survival rates and sex, age, and HbsAg of the patients (P > 0.05). In terms of pathological parameters, the 2-year and 3-year survival rates were significantly different according to the presence of a tumor capsule, degree of liver cirrhosis, satellite or focal lesions, hepatic vein thrombosis, portal vein tumor thrombus, and intraoperative blood loss (P < 0.05). CONCLUSION: The effectiveness of surgical resection for complex hepatocellular carcinoma may be affected by factors such as the presence of a tumor capsule, cirrhosis degree, satellite or focal lesions, hepatic vein embolization, portal vein tumor thrombus, and intraoperative blood loss. Therefore, these factors should be controlled and prevented during surgery to help improve patient survival after surgery.
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spelling pubmed-70525572020-03-06 Effectiveness of surgical resection for complicated liver cancer and its influencing factors: A retrospective study Yu, Jian Wu, Zhi-Zheng Li, Teng Xu, Ying Zhao, Yu-Cheng Zhang, Bo-Lun Tian, Hu World J Clin Cases Retrospective Study BACKGROUND: Surgical resection is the preferred method for patients with complex liver cancer. But the tumor is in a special position, the surgery is highly risky, postoperative complications can easily occur, and the prognosis is not ideal. AIM: To investigate the effectiveness of surgical resection for complex liver cancer and its influencing factors. METHODS: Fifty-seven patients who had complicated liver cancer and underwent surgical resection at our hospital from August 2015 to August 2016 were enrolled in this study. All patients were followed for three years, and their postoperative complications, survival, and factors that impacted their survival were analyzed. RESULTS: The total incidence of postoperative complications was 45.61%, and the incidence of pleural effusion was the highest at 28.07%. There were no correlations between the 2-year and 3-year survival rates and sex, age, and HbsAg of the patients (P > 0.05). In terms of pathological parameters, the 2-year and 3-year survival rates were significantly different according to the presence of a tumor capsule, degree of liver cirrhosis, satellite or focal lesions, hepatic vein thrombosis, portal vein tumor thrombus, and intraoperative blood loss (P < 0.05). CONCLUSION: The effectiveness of surgical resection for complex hepatocellular carcinoma may be affected by factors such as the presence of a tumor capsule, cirrhosis degree, satellite or focal lesions, hepatic vein embolization, portal vein tumor thrombus, and intraoperative blood loss. Therefore, these factors should be controlled and prevented during surgery to help improve patient survival after surgery. Baishideng Publishing Group Inc 2020-02-26 2020-02-26 /pmc/articles/PMC7052557/ /pubmed/32149057 http://dx.doi.org/10.12998/wjcc.v8.i4.736 Text en ©The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved. http://creativecommons.org/licenses/by-nc/4.0/ This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial.
spellingShingle Retrospective Study
Yu, Jian
Wu, Zhi-Zheng
Li, Teng
Xu, Ying
Zhao, Yu-Cheng
Zhang, Bo-Lun
Tian, Hu
Effectiveness of surgical resection for complicated liver cancer and its influencing factors: A retrospective study
title Effectiveness of surgical resection for complicated liver cancer and its influencing factors: A retrospective study
title_full Effectiveness of surgical resection for complicated liver cancer and its influencing factors: A retrospective study
title_fullStr Effectiveness of surgical resection for complicated liver cancer and its influencing factors: A retrospective study
title_full_unstemmed Effectiveness of surgical resection for complicated liver cancer and its influencing factors: A retrospective study
title_short Effectiveness of surgical resection for complicated liver cancer and its influencing factors: A retrospective study
title_sort effectiveness of surgical resection for complicated liver cancer and its influencing factors: a retrospective study
topic Retrospective Study
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7052557/
https://www.ncbi.nlm.nih.gov/pubmed/32149057
http://dx.doi.org/10.12998/wjcc.v8.i4.736
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