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Antenatal sildenafil citrate treatment increases offspring blood pressure in the placental-specific Igf2 knockout mouse model of FGR
Fetal growth restriction (FGR), where a fetus fails to reach its genetic growth potential, affects up to 8% of pregnancies and is a major risk factor for stillbirth and adulthood morbidity. There are currently no treatments for FGR, but candidate therapies include the phosphodiesterase-5 inhibitor s...
Autores principales: | Renshall, L. J., Cottrell, E. C., Cowley, E., Sibley, C. P., Baker, P. N., Thorstensen, E. B., Greenwood, S. L., Wareing, M., Dilworth, M. R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Physiological Society
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7052623/ https://www.ncbi.nlm.nih.gov/pubmed/31809211 http://dx.doi.org/10.1152/ajpheart.00568.2019 |
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