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Antenatal sildenafil citrate treatment increases offspring blood pressure in the placental-specific Igf2 knockout mouse model of FGR

Fetal growth restriction (FGR), where a fetus fails to reach its genetic growth potential, affects up to 8% of pregnancies and is a major risk factor for stillbirth and adulthood morbidity. There are currently no treatments for FGR, but candidate therapies include the phosphodiesterase-5 inhibitor s...

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Detalles Bibliográficos
Autores principales: Renshall, L. J., Cottrell, E. C., Cowley, E., Sibley, C. P., Baker, P. N., Thorstensen, E. B., Greenwood, S. L., Wareing, M., Dilworth, M. R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Physiological Society 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7052623/
https://www.ncbi.nlm.nih.gov/pubmed/31809211
http://dx.doi.org/10.1152/ajpheart.00568.2019

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