Cargando…

Modeling pulmonary fibrosis through bleomycin delivered by osmotic minipump: a new histomorphometric method of evaluation

The systemic delivery of bleomycin (BLM) to mice through subcutaneously implanted osmotic minipumps may be used to experimentally mimic the typical features of systemic sclerosis and related interstitial lung diseases. The published studies on this model principally have focused on induced dermal mo...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ravanetti, Francesca, Ragionieri, Luisa, Ciccimarra, Roberta, Ruscitti, Francesca, Pompilio, Daniela, Gazza, Ferdinando, Villetti, Gino, Cacchioli, Antonio, Stellari, Fabio F.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Physiological Society 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7052681/ https://www.ncbi.nlm.nih.gov/pubmed/31851533 http://dx.doi.org/10.1152/ajplung.00311.2019

Ejemplares similares

SSC-ILD mouse model induced by osmotic minipump delivered bleomycin: effect of Nintedanib
por: Ravanetti, Francesca, et al.
Publicado: (2021)

Heterologous Matrix Metalloproteinase Gene Promoter Activity Allows In Vivo Real-time Imaging of Bleomycin-Induced Lung Fibrosis in Transiently Transgenized Mice
por: Stellari, Fabio Franco, et al.
Publicado: (2017)

In-vivo lung fibrosis staging in a bleomycin-mouse model: a new micro-CT guided densitometric approach
por: Mecozzi, Laura, et al.
Publicado: (2020)

Longitudinal assessment of bleomycin-induced lung fibrosis by Micro-CT correlates with histological evaluation in mice
por: Ruscitti, Francesca, et al.
Publicado: (2017)

Proteomic Fingerprint of Lung Fibrosis Progression and Response to Therapy in Bleomycin-Induced Mouse Model
por: Principi, Lucrezia, et al.
Publicado: (2023)

Quantification of Lung Fibrosis in IPF-Like Mouse Model and Pharmacological Response to Treatment by Micro-Computed Tomography
por: Ruscitti, Francesca, et al.
Publicado: (2020)

Surfactant replacement therapy in combination with different non-invasive ventilation techniques in spontaneously-breathing, surfactant-depleted adult rabbits
por: Ricci, Francesca, et al.
Publicado: (2018)

Indocyanine-enhanced mouse model of bleomycin-induced lung fibrosis with hallmarks of progressive emphysema
por: Grandi, Andrea, et al.
Publicado: (2023)

The rapid hydrolysis of chlordiazepoxide to demoxepam may affect the outcome of chronic osmotic minipump studies
por: Vinkers, Christiaan H., et al.
Publicado: (2010)

The normal and fibrotic mouse lung classified by spatial proteomic analysis
por: Ciccimarra, Roberta, et al.
Publicado: (2022)

Alfaxalone and Dexmedetomidine as an Alternative to Gas Anesthesia for Micro-CT Lung Imaging in a Bleomycin-Induced Pulmonary Fibrosis Murine Model
por: Ferrini, Erica, et al.
Publicado: (2020)

In vivo monitoring of lung inflammation in CFTR-deficient mice
por: Stellari, Fabio, et al.
Publicado: (2016)

Pivotal role of micro-CT technology in setting up an optimized lung fibrosis mouse model for drug screening
por: Khalajzeyqami, Zahra, et al.
Publicado: (2022)

Monitoring inflammation and airway remodeling by fluorescence molecular tomography in a chronic asthma model
por: Stellari, Fabio, et al.
Publicado: (2015)

Time-resolved transcriptomic profiling of the developing rabbit’s lungs: impact of premature birth and implications for modelling bronchopulmonary dysplasia
por: Storti, Matteo, et al.
Publicado: (2023)

CHF6001 Inhibits NF-κB Activation and Neutrophilic Recruitment in LPS-Induced Lung Inflammation in Mice
por: Stellari, Fabio F., et al.
Publicado: (2019)

Enlightened Mannhemia haemolytica lung inflammation in bovinized mice
por: Stellari, Fabio Franco, et al.
Publicado: (2014)

In vivo imaging of the lung inflammatory response to Pseudomonas aeruginosa and its modulation by azithromycin
por: Stellari, Fabio, et al.
Publicado: (2015)

Azithromycin inhibits nuclear factor-κB activation during lung inflammation: an in vivo imaging study
por: Stellari, Fabio F, et al.
Publicado: (2014)

A fully automated micro‑CT deep learning approach for precision preclinical investigation of lung fibrosis progression and response to therapy
por: Buccardi, Martina, et al.
Publicado: (2023)

Chitosan-based scaffold modified with D-(+) raffinose for cartilage repair: an in vivo study
por: Ravanetti, Francesca, et al.
Publicado: (2015)

Chronic Methylglyoxal Infusion by Minipump Causes Pancreatic β-Cell Dysfunction and Induces Type 2 Diabetes in Sprague-Dawley Rats
por: Dhar, Arti, et al.
Publicado: (2011)

“Over-inlay” block graft and differential morphometry: a novel block graft model to study bone regeneration and host-to-graft interfaces in rats
por: Ghiacci, Giulia, et al.
Publicado: (2016)

Persistency of Mesenchymal Stromal/Stem Cells in Lungs
por: Ferrini, Erica, et al.
Publicado: (2021)

In Vivo Imaging of Transiently Transgenized Mice with a Bovine Interleukin 8 (CXCL8) Promoter/Luciferase Reporter Construct
por: Stellari, Fabio Franco, et al.
Publicado: (2012)

Age-dependent histomorphometric evolution of the corpus spongiosum
por: Pigatto, Gino, et al.
Publicado: (2021)

Localization of Peripheral Autonomic Neurons Innervating the Boar Urinary Bladder Trigone and Neurochemical Features of the Sympathetic Component
por: Ragionieri, L., et al.
Publicado: (2013)

Phosphodiesterase 4 inhibitors attenuate virus‐induced activation of eosinophils from asthmatics without affecting virus binding
por: Sabogal Piñeros, Yanaika Shari, et al.
Publicado: (2020)

Time-course transcriptome analysis of a double challenge bleomycin-induced lung fibrosis rat model uncovers ECM homoeostasis-related translationally relevant genes
por: Bonatti, Martina, et al.
Publicado: (2023)

Special Issue: Innovative Pasta with High Nutritional and Health Potential
por: Gazza, Laura, et al.
Publicado: (2022)

The Contribution of Minor Cereals to Sustainable Diets and Agro-Food Biodiversity
por: Gazza, Laura, et al.
Publicado: (2023)

Histomorphometric Analysis of Experimental Disc Degeneration
por: Vialle, Emiliano Neves, et al.
Publicado: (2012)

Immune Mechanisms of Pulmonary Fibrosis with Bleomycin
por: Ishida, Yuko, et al.
Publicado: (2023)

Histological, histomorphometric and microtomographic analyses of retrieval hip resurfacing arthroplasty failed at different times
por: Salamanna, Francesca, et al.
Publicado: (2013)

Innovative Milling Processes to Improve the Technological and Nutritional Quality of Parboiled Brown Rice Pasta from Contrasting Amylose Content Cultivars
por: Taddei, Federica, et al.
Publicado: (2021)

Histomorphometric changes of small intestine in pregnant rat
por: Sabet Sarvestani, Fatemeh, et al.
Publicado: (2015)

Histomorphometric study of brachiocephalic artery of Japanese quail
por: Shariati, Sarah, et al.
Publicado: (2015)

Hip Osteoarthritis and Osteoporosis: Clinical and Histomorphometric Considerations
por: Tarantino, Umberto, et al.
Publicado: (2014)

Regions of the human renal artery: histomorphometric analysis
por: Mompeó-Corredera, Blanca, et al.
Publicado: (2022)

Osmotic behavior and permeability of osmotically lysed mitochondria
Publicado: (1976)

Cannot write session to /tmp/vufind_sessions/sess_sk6mhu8fqknsb5cqmfl1hi3an0