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Valproic Acid and Epilepsy: From Molecular Mechanisms to Clinical Evidences
After more than a century from its discovery, valproic acid (VPA) still represents one of the most efficient antiepi-leptic drugs (AEDs). Pre and post-synaptic effects of VPA depend on a very broad spectrum of actions, including the regu-lation of ionic currents and the facilitation of GABAergic ove...
Autores principales: | Romoli, Michele, Mazzocchetti, Petra, D’Alonzo, Renato, Siliquini, Sabrina, Rinaldi, Victoria Elisa, Verrotti, Alberto, Calabresi, Paolo, Costa, Cinzia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Bentham Science Publishers
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7052829/ https://www.ncbi.nlm.nih.gov/pubmed/30592252 http://dx.doi.org/10.2174/1570159X17666181227165722 |
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