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Histone deacetylase inhibitor MGCD0103 causes cell cycle arrest, apoptosis, and autophagy in liver cancer cells

Background: Liver cancer is a common cause of cancer-related death all over the world. MGCD0103, a histone deacetylase inhibitor, exerts antitumor effect on various cancers. However, its role in liver cancer remains unclear. Methods: The effect of MGCD0103 on HepG2 and Huh7 cells was verified by sev...

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Detalles Bibliográficos
Autores principales: Liao, Bo, Sun, Quan, Yuan, Yufeng, Yin, Yuchun, Qiao, Jianguo, Jiang, Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7052879/
https://www.ncbi.nlm.nih.gov/pubmed/32194803
http://dx.doi.org/10.7150/jca.34091