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FGD1 promotes tumor progression and regulates tumor immune response in osteosarcoma via inhibiting PTEN activity
Rationale: Mesenchymal cell-derived osteosarcoma is a rare malignant bone tumor affecting children and adolescents. PTEN down-regulation or function-loss mutation is associated with the aggressive of osteosarcoma. Explicating the regulatory mechanism of PTEN might highlight new targets for improving...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Ivyspring International Publisher
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7052884/ https://www.ncbi.nlm.nih.gov/pubmed/32194840 http://dx.doi.org/10.7150/thno.41279 |