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Mitochondrial PAK6 inhibits prostate cancer cell apoptosis via the PAK6-SIRT4-ANT2 complex

Rationale: P21-activated kinase 6 (PAK6) is a member of the class II PAKs family, which is a conserved family of serine/threonine kinases. Although the effects of PAK6 on many malignancies, especially in prostate cancer, have been studied for a long time, the role of PAK6 in mitochondria remains unk...

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Detalles Bibliográficos
Autores principales: Li, Tingting, Li, Yang, Liu, Tong, Hu, Bingtao, Li, Jiabin, Liu, Chen, Liu, Tao, Li, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7052886/
https://www.ncbi.nlm.nih.gov/pubmed/32194820
http://dx.doi.org/10.7150/thno.42874

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