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Upregulation of neuronal PGC-1α ameliorates cognitive impairment induced by chronic cerebral hypoperfusion
Rationale: Mitochondrial dysfunction and oxidative stress occur in vascular dementia (VaD), but the specific molecular mechanism regulating these events remains unclear. Peroxisome proliferator-activated receptor-γ co-activator-1α (PGC-1α) is a master regulator for mitochondrial function. This study...
Autores principales: | Han, Bin, Jiang, Wei, Liu, Haijie, Wang, Junjie, Zheng, Kai, Cui, Pan, Feng, Yan, Dang, Chun, Bu, Yali, Wang, Qing Mei, Ju, Zhenyu, Hao, Junwei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ivyspring International Publisher
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7052889/ https://www.ncbi.nlm.nih.gov/pubmed/32194838 http://dx.doi.org/10.7150/thno.37119 |
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