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HIF-1ɑ-regulated miR-1275 maintains stem cell-like phenotypes and promotes the progression of LUAD by simultaneously activating Wnt/β-catenin and Notch signaling

Rationale: Cancer stem cells (CSCs) are considered to be essential for tumorigenesis, recurrence, and metastasis and therefore serve as a biomarker for tumor progression in diverse cancers. Recent studies have illustrated that specific miRNAs exhibit novel therapeutic potential by controlling CSC pr...

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Detalles Bibliográficos
Autores principales: Jiang, Neng, Zou, Chang, Zhu, Ying, Luo, Yifeng, Chen, Lili, Lei, Yiyan, Tang, Kejing, Sun, Yu, Zhang, Wenhui, Li, Shuhua, He, Qiong, Zhou, Jianwen, Chen, Yangshan, Luo, Jiping, Jiang, Wenting, Ke, Zunfu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7052895/
https://www.ncbi.nlm.nih.gov/pubmed/32194819
http://dx.doi.org/10.7150/thno.41120