Targeting microtubules sensitizes drug resistant lung cancer cells to lysosomal pathway inhibitors

Oncogene-addicted cancers are predominantly driven by specific oncogenic pathways and display initial exquisite sensitivity to designer therapies, but eventually become refractory to treatments. Clear understanding of lung tumorigenic mechanisms is essential for improved therapies. Methods: Lysosome...

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Detalles Bibliográficos
Autores principales: Chin, Tan-Min, Boopathy, Gandhi T. K., Man, Ellen P.S., Clohessy, John G., Csizmadia, Eva, Quinlan, Margaret P, Putti, Thomas, Wan, Seow-Ching, Xie, Chen, Ali, Azhar, Wai, Fhu Chee, Ong, Yan Shan, Goh, Boon-Cher, Settleman, Jeff, Hong, Wanjin, Levantini, Elena, Tenen, Daniel G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2020
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7052910/
https://www.ncbi.nlm.nih.gov/pubmed/32194831
http://dx.doi.org/10.7150/thno.38729

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