Therapeutic Rationale to Target Highly Expressed Aurora kinase A Conferring Poor Prognosis in Cholangiocarcinoma

Background: Cholangiocarcinoma is a highly lethal neoplasm for which the currently available chemotherapeutic agents are suboptimal. Numerous studies show that alterations in expression of genes related to mitotic spindle and mitotic checkpoint are involved in chromosomal instability and tumor progr...

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Detalles Bibliográficos
Autores principales: Ding, Xiwei, Huang, Tianlu, Peng, Chunyan, Ahn, Keun Soo, Andersen, Jesper B, Lewinska, Monika, Cao, Yu, Xu, Guifang, Chen, Gang, Kong, Bo, Friess, Helmut, Shen, Shanshan, Roberts, Lewis R, Wang, Lei, Zou, Xiaoping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2020
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7052919/
https://www.ncbi.nlm.nih.gov/pubmed/32127951
http://dx.doi.org/10.7150/jca.31989

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