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Basonuclin 1 deficiency causes testicular premature aging: BNC1 cooperates with TAF7L to regulate spermatogenesis

Basonuclin (BNC1) is expressed primarily in proliferative keratinocytes and gametogenic cells. However, its roles in spermatogenesis and testicular aging were not clear. Previously we discovered a heterozygous BNC1 truncation mutation in a premature ovarian insufficiency pedigree. In this study, we...

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Detalles Bibliográficos
Autores principales: Li, Jing-Yi, Liu, Yi-Feng, Xu, Hai-Yan, Zhang, Jun-Yu, Lv, Ping-Ping, Liu, Miao-E, Ying, Yan-Yun, Qian, Ye-Qing, Li, Kun, Li, Cheng, Huang, Yun, Xu, Gu-Feng, Ding, Guo-Lian, Mao, Yu-Chan, Xu, Chen-Ming, Liu, Xin-Mei, Sheng, Jian-Zhong, Zhang, Dan, Huang, He-Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7052986/
https://www.ncbi.nlm.nih.gov/pubmed/31065688
http://dx.doi.org/10.1093/jmcb/mjz035