Cargando…

Integrative systems and functional analyses reveal a role of dopaminergic signaling in myelin pathogenesis

BACKGROUND: Myelin sheaths surrounding axons are critical for electrical signal transmission in the central nervous system (CNS). Diseases with myelin defects such as multiple sclerosis (MS) are devastating neurological conditions for which few effective treatments are available. Dysfunction of the...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ding, Sujun, Gu, Yun, Cai, Yunyun, Cai, Meijuan, Yang, Tuo, Bao, Shuangxi, Shen, Weixing, Ni, Xuejun, Chen, Gang, Xing, Lingyan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7053059/ https://www.ncbi.nlm.nih.gov/pubmed/32122379 http://dx.doi.org/10.1186/s12967-020-02276-1

Ejemplares similares

Identification of genes associated with sudden cardiac death: a network- and pathway-based approach
por: Wei, Jinhuan, et al.
Publicado: (2021)

EphA4 Negatively Regulates Myelination by Inhibiting Schwann Cell Differentiation in the Peripheral Nervous System
por: Chen, Ruyue, et al.
Publicado: (2019)

The transcription factor Stat-1 is essential for Schwann cell differentiation, myelination and myelin sheath regeneration
por: Xu, Jinghui, et al.
Publicado: (2023)

Dopaminergic Neuronal Imaging in Genetic Parkinson's Disease: Insights into Pathogenesis
por: McNeill, Alisdair, et al.
Publicado: (2013)

The Role of the Renal Dopaminergic System and Oxidative Stress in the Pathogenesis of Hypertension
por: Qaddumi, Waleed N., et al.
Publicado: (2021)

Epigenetic Modifiers Are Necessary but Not Sufficient for Reprogramming Non-Myelinating Cells into Myelin Gene-Expressing Cells
por: Liu, Jia, et al.
Publicado: (2010)

New Insights in the Pathogenesis of Multiple Sclerosis—Role of Acrolein in Neuronal and Myelin Damage
por: Tully, Melissa, et al.
Publicado: (2013)

Expression of myelin transcription factor 1 and lamin B receptor mediate neural progenitor fate transition in the zebrafish spinal cord pMN domain
por: Xing, Lingyan, et al.
Publicado: (2022)

Polarization and Myelination in Myelinating Glia
por: Masaki, Toshihiro
Publicado: (2012)

Myelin lipid metabolism and its role in myelination and myelin maintenance
por: Barnes-Vélez, Joseph A., et al.
Publicado: (2022)

Overview of myelin, major myelin lipids, and myelin-associated proteins
por: Kister, Alexander, et al.
Publicado: (2023)

Identification of immune-related hub genes contributing to the pathogenesis, diagnosis, and remission of ulcerative colitis by integrated bioinformatic analyses
por: Zhou, Lingna, et al.
Publicado: (2023)

Myelin-Specific Cd8 T Cells in the Pathogenesis of Experimental Allergic Encephalitis and Multiple Sclerosis
por: Steinman, Lawrence
Publicado: (2001)

The Etv1/Er81 transcription factor coordinates myelination-related genes to regulate Schwann cell differentiation and myelination
por: Askar, Parizat, et al.
Publicado: (2022)

Autophagic degradation of CNS myelin maintains axon integrity
por: Ktena, Niki, et al.
Publicado: (2022)

Identification of Transcriptional Modules and Key Genes in Chickens Infected with Salmonella enterica Serovar Pullorum Using Integrated Coexpression Analyses
por: Liu, Bao-Hong, et al.
Publicado: (2017)

Dopaminergic reward system: a short integrative review
por: Arias-Carrión, Oscar, et al.
Publicado: (2010)

Dopaminergic intracellular signal integrating proteins: relevance to schizophrenia
por: Souza, Bruno R., et al.
Publicado: (2006)

Engine Failure in Axo-Myelinic Signaling: A Potential Key Player in the Pathogenesis of Multiple Sclerosis
por: Bergaglio, Talia, et al.
Publicado: (2021)

Aldehyde Dehydrogenase 1 making molecular inroads into the differential vulnerability of nigrostriatal dopaminergic neuron subtypes in Parkinson’s disease
por: Cai, Huaibin, et al.
Publicado: (2014)

Molecular Regulation in Dopaminergic Neuron Development. Cues to Unveil Molecular Pathogenesis and Pharmacological Targets of Neurodegeneration
por: Volpicelli, Floriana, et al.
Publicado: (2020)

Connexin Hemichannels in Astrocytes: Role in CNS Disorders
por: Xing, LingYan, et al.
Publicado: (2019)

Synthesis and incorporation of myelin polypeptides into CNS myelin
Publicado: (1982)

Coronaviruses and Neuroantigens: myelin proteins, myelin genes
por: Talbot, Pierre J., et al.
Publicado: (2005)

Sex, myelin, and clinical characteristics of Parkinson’s disease
por: Cai, Jiayue, et al.
Publicado: (2023)

Comparative Genome and Transcriptome Integration Studies Reveal the Mechanism of Pectoral Muscle Development and Function in Pigeons
por: Hou, Haobin, et al.
Publicado: (2021)

The Drainage of Interstitial Fluid in the Deep Brain is Controlled by the Integrity of Myelination
por: Wang, Aibo, et al.
Publicado: (2019)

Astrocytes Are Required for Oligodendrocyte Survival and Maintenance of Myelin Compaction and Integrity
por: Tognatta, Reshmi, et al.
Publicado: (2020)

Microglia regulate central nervous system myelin growth and integrity
por: McNamara, Niamh B., et al.
Publicado: (2022)

Two different isoforms of osteopontin modulate myelination and axonal integrity
por: Nilsson, Gisela, et al.
Publicado: (2023)

Unbalanced calcium channel activity underlies selective vulnerability of nigrostriatal dopaminergic terminals in Parkinsonian mice
por: Sgobio, Carmelo, et al.
Publicado: (2019)

Serial Anti–Myelin Oligodendrocyte Glycoprotein Antibody Analyses and Outcomes in Children With Demyelinating Syndromes
por: Waters, Patrick, et al.
Publicado: (2019)

In actio optophysiological analyses reveal functional diversification of dopaminergic neurons in the nematode C. elegans
por: Tanimoto, Yuki, et al.
Publicado: (2016)

Investigation of the role of delayed-type-hypersensitivity responses to myelin in the pathogenesis of Theiler's virus-induced demyelinating disease.
por: Borrow, P, et al.
Publicado: (1998)

Clues from Crouzon: Insights into the potential role of growth factors in the pathogenesis of myelinated retinal nerve fibers
por: Garcia, Giancarlo A., et al.
Publicado: (2016)

Roles of the Functional Interaction between Brain Cholinergic and Dopaminergic Systems in the Pathogenesis and Treatment of Schizophrenia and Parkinson’s Disease
por: Acharya, Srijan, et al.
Publicado: (2021)

Altered Development of Mesencephalic Dopaminergic Neurons in SIDS: New Insights into Understanding Sudden Infant Death Pathogenesis
por: Lavezzi, Anna Maria
Publicado: (2021)

Inherited and acquired disorders of myelin: The underlying myelin pathology
por: Duncan, Ian D., et al.
Publicado: (2016)

Magnetic Resonance of Myelin Water: An in vivo Marker for Myelin
por: MacKay, Alex L., et al.
Publicado: (2016)

Microglia phagocytose myelin sheaths to modify developmental myelination
por: Hughes, Alexandria N., et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_76033o25j3v2m8dqnhm58qaka6