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Accurate targeted long-read DNA methylation and hydroxymethylation sequencing with TAPS

We present long-read Tet-assisted pyridine borane sequencing (lrTAPS) for targeted base-resolution sequencing of DNA methylation and hydroxymethylation in regions up to 10 kb from nanogram-level input. Compatible with both Oxford Nanopore and PacBio Single-Molecule Real-Time (SMRT) sequencing, lrTAP...

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Detalles Bibliográficos
Autores principales:	Liu, Yibin, Cheng, Jingfei, Siejka-Zielińska, Paulina, Weldon, Carika, Roberts, Hannah, Lopopolo, Maria, Magri, Andrea, D’Arienzo, Valentina, Harris, James M., McKeating, Jane A., Song, Chun-Xiao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Short Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7053107/ https://www.ncbi.nlm.nih.gov/pubmed/32127008 http://dx.doi.org/10.1186/s13059-020-01969-6

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