Utilizing minimally purified secreted rAAV for rapid and cost-effective manipulation of gene expression in the CNS

BACKGROUND: Recombinant adeno-associated virus (rAAV) is widely used in the neuroscience field to manipulate gene expression in the nervous system. However, a limitation to the use of rAAV vectors is the time and expense needed to produce them. To overcome this limitation, we evaluated whether unpur...

Descripción completa

Detalles Bibliográficos
Autores principales: Goodwin, Marshall S., Croft, Cara L., Futch, Hunter S., Ryu, Daniel, Ceballos-Diaz, Carolina, Liu, Xuefei, Paterno, Giavanna, Mejia, Catalina, Deng, Doris, Menezes, Kimberly, Londono, Laura, Arjona, Kefren, Parianos, Mary, Truong, Van, Rostonics, Eva, Hernandez, Amanda, Boye, Sanford L., Boye, Shannon E., Levites, Yona, Cruz, Pedro E., Golde, Todd E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Methodology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7053119/
https://www.ncbi.nlm.nih.gov/pubmed/32122372
http://dx.doi.org/10.1186/s13024-020-00361-z

Ejemplares similares

Ejemplares similares