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PARP inhibitors in pancreatic cancer: molecular mechanisms and clinical applications
Pancreatic cancer is a highly lethal disease with a poor prognosis, and existing therapies offer only limited effectiveness. Mutation gene sequencing has shown several gene associations that may account for its carcinogenesis, revealing a promising research direction. Poly (ADP-ribose) polymerase (P...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7053129/ https://www.ncbi.nlm.nih.gov/pubmed/32122376 http://dx.doi.org/10.1186/s12943-020-01167-9 |