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Cannabidiol Drugs Clinical Trial Outcomes and Adverse Effects
This review aims to present completed clinical trial data surrounding the medicinal benefits and potential side effects of the increasingly popular cannabidiol (CBD)-based drug products, specifically Epidiolex. The article is divided into two sections based on if the ailment being treated by this ca...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7053164/ https://www.ncbi.nlm.nih.gov/pubmed/32161538 http://dx.doi.org/10.3389/fphar.2020.00063 |
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author | Pauli, Christopher S. Conroy, Matthieu Vanden Heuvel, Brian D. Park, Sang-Hyuck |
author_facet | Pauli, Christopher S. Conroy, Matthieu Vanden Heuvel, Brian D. Park, Sang-Hyuck |
author_sort | Pauli, Christopher S. |
collection | PubMed |
description | This review aims to present completed clinical trial data surrounding the medicinal benefits and potential side effects of the increasingly popular cannabidiol (CBD)-based drug products, specifically Epidiolex. The article is divided into two sections based on if the ailment being treated by this cannabinoid is classified as either physiological or neurological conditions. In addition to describing the current status, we also examined the different primary and secondary outcomes recorded for each study, which varies greatly depending on the funding source of the clinical trial. With the recent FDA-approval of Epidiolex, this review mainly focused on trials involving this specific formulation since it is the only CBD-based drug currently available to clinicians, although all other clinically trialed CBD(A) drugs were also examined. We hope this review will help guide future research and clinical trials by providing the various outcomes measured in a single review. |
format | Online Article Text |
id | pubmed-7053164 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-70531642020-03-11 Cannabidiol Drugs Clinical Trial Outcomes and Adverse Effects Pauli, Christopher S. Conroy, Matthieu Vanden Heuvel, Brian D. Park, Sang-Hyuck Front Pharmacol Pharmacology This review aims to present completed clinical trial data surrounding the medicinal benefits and potential side effects of the increasingly popular cannabidiol (CBD)-based drug products, specifically Epidiolex. The article is divided into two sections based on if the ailment being treated by this cannabinoid is classified as either physiological or neurological conditions. In addition to describing the current status, we also examined the different primary and secondary outcomes recorded for each study, which varies greatly depending on the funding source of the clinical trial. With the recent FDA-approval of Epidiolex, this review mainly focused on trials involving this specific formulation since it is the only CBD-based drug currently available to clinicians, although all other clinically trialed CBD(A) drugs were also examined. We hope this review will help guide future research and clinical trials by providing the various outcomes measured in a single review. Frontiers Media S.A. 2020-02-25 /pmc/articles/PMC7053164/ /pubmed/32161538 http://dx.doi.org/10.3389/fphar.2020.00063 Text en Copyright © 2020 Pauli, Conroy, Vanden Heuvel and Park http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Pharmacology Pauli, Christopher S. Conroy, Matthieu Vanden Heuvel, Brian D. Park, Sang-Hyuck Cannabidiol Drugs Clinical Trial Outcomes and Adverse Effects |
title | Cannabidiol Drugs Clinical Trial Outcomes and Adverse Effects |
title_full | Cannabidiol Drugs Clinical Trial Outcomes and Adverse Effects |
title_fullStr | Cannabidiol Drugs Clinical Trial Outcomes and Adverse Effects |
title_full_unstemmed | Cannabidiol Drugs Clinical Trial Outcomes and Adverse Effects |
title_short | Cannabidiol Drugs Clinical Trial Outcomes and Adverse Effects |
title_sort | cannabidiol drugs clinical trial outcomes and adverse effects |
topic | Pharmacology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7053164/ https://www.ncbi.nlm.nih.gov/pubmed/32161538 http://dx.doi.org/10.3389/fphar.2020.00063 |
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