Risk factors of the efficacy of hepatitis B vaccine in health-care workers

BACKGROUND: Conventional hepatitis B virus vaccination fails to achieve efficient protection in about 5%–10% of the world population. Different factors influence the immunogenicity of hepatitis B vaccine. This study aimed to evaluate these factors in health-care workers. MATERIALS AND METHODS: This...

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Autores principales: Salehi, Hassan, Salehi, Marzieh, Kalbasi, Nader, Salehi, Maryam, Sharifian, Jalil, Salehi, Mohammad Mahdi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2020
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7053165/
https://www.ncbi.nlm.nih.gov/pubmed/32174987
http://dx.doi.org/10.4103/jrms.JRMS_1054_18
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author Salehi, Hassan
Salehi, Marzieh
Kalbasi, Nader
Salehi, Maryam
Sharifian, Jalil
Salehi, Mohammad Mahdi
author_facet Salehi, Hassan
Salehi, Marzieh
Kalbasi, Nader
Salehi, Maryam
Sharifian, Jalil
Salehi, Mohammad Mahdi
author_sort Salehi, Hassan
collection PubMed
description BACKGROUND: Conventional hepatitis B virus vaccination fails to achieve efficient protection in about 5%–10% of the world population. Different factors influence the immunogenicity of hepatitis B vaccine. This study aimed to evaluate these factors in health-care workers. MATERIALS AND METHODS: This was a descriptive study which was implemented among 140 of medical and dental staff working as health-care workers who were low responder after vaccination entered the study. RESULTS: Age (>40 years), weight (body mass index >25), immunodeficiency diseases, (primary immune deficiency and immunosuppressant drugs), diabetes mellitus, and smoking were the important factors. CONCLUSION: In the high-risk group of hepatitis B disease, the risk factors of immunogenicity must be evaluated at vaccination and check titers of antibody after vaccination.
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spelling pubmed-70531652020-03-13 Risk factors of the efficacy of hepatitis B vaccine in health-care workers Salehi, Hassan Salehi, Marzieh Kalbasi, Nader Salehi, Maryam Sharifian, Jalil Salehi, Mohammad Mahdi J Res Med Sci Short Communication BACKGROUND: Conventional hepatitis B virus vaccination fails to achieve efficient protection in about 5%–10% of the world population. Different factors influence the immunogenicity of hepatitis B vaccine. This study aimed to evaluate these factors in health-care workers. MATERIALS AND METHODS: This was a descriptive study which was implemented among 140 of medical and dental staff working as health-care workers who were low responder after vaccination entered the study. RESULTS: Age (>40 years), weight (body mass index >25), immunodeficiency diseases, (primary immune deficiency and immunosuppressant drugs), diabetes mellitus, and smoking were the important factors. CONCLUSION: In the high-risk group of hepatitis B disease, the risk factors of immunogenicity must be evaluated at vaccination and check titers of antibody after vaccination. Wolters Kluwer - Medknow 2020-02-20 /pmc/articles/PMC7053165/ /pubmed/32174987 http://dx.doi.org/10.4103/jrms.JRMS_1054_18 Text en Copyright: © 2020 Journal of Research in Medical Sciences http://creativecommons.org/licenses/by-nc-sa/4.0 This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Short Communication
Salehi, Hassan
Salehi, Marzieh
Kalbasi, Nader
Salehi, Maryam
Sharifian, Jalil
Salehi, Mohammad Mahdi
Risk factors of the efficacy of hepatitis B vaccine in health-care workers
title Risk factors of the efficacy of hepatitis B vaccine in health-care workers
title_full Risk factors of the efficacy of hepatitis B vaccine in health-care workers
title_fullStr Risk factors of the efficacy of hepatitis B vaccine in health-care workers
title_full_unstemmed Risk factors of the efficacy of hepatitis B vaccine in health-care workers
title_short Risk factors of the efficacy of hepatitis B vaccine in health-care workers
title_sort risk factors of the efficacy of hepatitis b vaccine in health-care workers
topic Short Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7053165/
https://www.ncbi.nlm.nih.gov/pubmed/32174987
http://dx.doi.org/10.4103/jrms.JRMS_1054_18
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