Cargando…

Synthesis and inhibitory activity of N-acetylpyrrolidine derivatives on α-glucosidase and α-amylase

BACKGROUND AND PURPOSE: Carbohydrate hydrolysis enzymes including α-glucosidase and α-amylase are related to type 2 diabetes mellitus. The inhibiting of these enzymes might use for type 2 diabetes mellitus treatment. EXPERIMENTAL APPROACH: N-substituted-acetylpyrrolidine linked with -benzyl- (N-(ben...

Descripción completa

Detalles Bibliográficos
Autores principales:	Sansenya, Sompong, Winyakul, Chankan, Nanok, Kesinee, Phutdhawong, Waya S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Wolters Kluwer - Medknow 2020
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7053292/ https://www.ncbi.nlm.nih.gov/pubmed/32180813 http://dx.doi.org/10.4103/1735-5362.278711

Ejemplares similares

Inhibitory Efficacy of Cycloartenyl Ferulate against α-Glucosidase and α-Amylase and Its Increased Concentration in Gamma-Irradiated Rice (Germinated Rice)
por: Sansenya, Sompong, et al.
Publicado: (2023)

2,5-Diketopiperazine Derivatives as Potential Anti-Influenza (H5N2) Agents: Synthesis, Biological Evaluation, and Molecular Docking Study
por: Winyakul, Chanakan, et al.
Publicado: (2022)

In vitro inhibitory effects of plant-based foods and their combinations on intestinal α-glucosidase and pancreatic α-amylase
por: Adisakwattana, Sirichai, et al.
Publicado: (2012)

Influence of gallic acid on α-amylase and α-glucosidase inhibitory properties of acarbose
por: Oboh, Ganiyu, et al.
Publicado: (2016)

Spiroindolone Analogues as Potential Hypoglycemic with Dual Inhibitory Activity on α-Amylase and α-Glucosidase
por: Altowyan, Mezna Saleh, et al.
Publicado: (2019)

In vitro α-amylase and α-glucosidase inhibitory effects and cytotoxic activity of Albizia antunesiana extracts
por: Chipiti, Talent, et al.
Publicado: (2015)

The α-amylase and α-glucosidase inhibitory activities of the dichloromethane extracts and constituents of Ferulago bracteata roots
por: Karakaya, Songül, et al.
Publicado: (2017)

Antioxidant, α-Amylase and α-Glucosidase Inhibitory Activities and Potential Constituents of Canarium tramdenum Bark
por: Quan, Nguyen Van, et al.
Publicado: (2019)

Synthesis and Biological Activity Evaluation of Coumarin-3-Carboxamide Derivatives
por: Phutdhawong, Weerachai, et al.
Publicado: (2021)

In vitro α -amylase and α-glucosidase inhibitory potential of Trigonella foenum-graecum leaves extract
por: Ganeshpurkar, Aditya, et al.
Publicado: (2013)

In Vitro Inhibitory Effects of Organic Acids Identified in Commercial Vinegars on α-Amylase and α-Glucosidase
por: Noh, Young-Hee, et al.
Publicado: (2020)

In vitro and in vivo inhibitory effects of Carica papaya seed on α-amylase and α-glucosidase enzymes
por: Agada, Reuben, et al.
Publicado: (2020)

Synthesis and Investigation of Tetrahydro-β-carboline Derivatives as Inhibitors of Plant Pathogenic Fungi
por: Buaban, Koonchira, et al.
Publicado: (2021)

Development of an antidiabetic formulation (ADJ6) and its inhibitory activity against α-amylase and α-glucosidase
por: Duraiswamy, Anand, et al.
Publicado: (2015)

Five New Pregnane Glycosides from Gymnema sylvestre and Their α-Glucosidase and α-Amylase Inhibitory Activities
por: Kiem, Phan Van, et al.
Publicado: (2020)

Structural changes and molecular mechanism study on the inhibitory activity of epigallocatechin against α-glucosidase and α-amylase
por: Man, Ziyi, et al.
Publicado: (2022)

Synthesis and bioactivities evaluation of oleanolic acid oxime ester derivatives as α-glucosidase and α-amylase inhibitors
por: Deng, Xu-Yang, et al.
Publicado: (2022)

A Review of the In Vitro Inhibition of α-Amylase and α-Glucosidase by Chalcone Derivatives
por: Tran, Thanh-Dao, et al.
Publicado: (2023)

Molecular Modeling and Synthesis of Indoline-2,3-dione-Based Benzene Sulfonamide Derivatives and Their Inhibitory Activity against α-Glucosidase and α-Amylase Enzymes
por: Rasheed, Liaqat, et al.
Publicado: (2023)

Synthesis and Inhibitory Effect of Some Indole‐Pyrimidine Based Hybrid Heterocycles on α‐Glucosidase and α‐Amylase as Potential Hypoglycemic Agents
por: Badria, Farid A., et al.
Publicado: (2019)

Linking the Phytochemicals and the α-Glucosidase and α-Amylase Enzyme Inhibitory Effects of Nigella sativa Seed Extracts
por: Tiji, Salima, et al.
Publicado: (2021)

In Vitro and In Silico Evaluation for the Inhibitory Action of O. basilicum Methanol Extract on α-Glucosidase and α-Amylase
por: Shanak, Siba, et al.
Publicado: (2021)

Chemical Characterization, α-Glucosidase, α-Amylase and Lipase Inhibitory Properties of the Australian Honey Bee Propolis
por: Uddin, Sabah, et al.
Publicado: (2022)

α-Amylase and α-Glucosidase Inhibitory Activities of Chemical Constituents from Wedelia chinensis (Osbeck.) Merr. Leaves
por: Thao, Nguyen Phuong, et al.
Publicado: (2018)

In vitro α-amylase and α-glucosidase Inhibitory and Cytotoxic Activities of Extracts from Cissus cornifolia Planch Parts
por: Chipiti, Talent, et al.
Publicado: (2017)

The Application of Ultrasound in Honey: Antioxidant Activity, Inhibitory Effect on α-amylase and α-glucosidase, and In Vitro Digestibility Assessment
por: Peláez-Acero, Armando, et al.
Publicado: (2022)

Synthesis of Benzylidene Analogs of Oleanolic Acid as Potential α-Glucosidase and α-Amylase Inhibitors
por: Ke, Jun-Jie, et al.
Publicado: (2022)

Momilactones A and B Are α-Amylase and α-Glucosidase Inhibitors
por: Quan, Nguyen Van, et al.
Publicado: (2019)

Dietary Polyphenols as Natural Inhibitors of α-Amylase and α-Glucosidase
por: Ćorković, Ina, et al.
Publicado: (2022)

Synthesis and In Vitro α-Amylase and α-Glucosidase Dual Inhibitory Activities of 1,2,4-Triazole-Bearing bis-Hydrazone Derivatives and Their Molecular Docking Study
por: Khan, Imran, et al.
Publicado: (2023)

Inhibitory Activities of Cyanidin and Its Glycosides and Synergistic Effect with Acarbose against Intestinal α-Glucosidase and Pancreatic α-Amylase
por: Akkarachiyasit, Sarinya, et al.
Publicado: (2010)

In-vitro α-amylase and α-glucosidase inhibitory activity of Adiantum caudatum Linn. and Celosia argentea Linn. extracts and fractions
por: Telagari, Madhusudhan, et al.
Publicado: (2015)

Effect of cooking on glycemic index, antioxidant activities, α‐amylase, and α‐glucosidase inhibitory properties of two rice varieties
por: Adedayo, Bukola C., et al.
Publicado: (2018)

In vitro α-amylase, α-glucosidase, lipase inhibitory and cytotoxic activities of tuber extracts of Kedrostis africana (L.) Cogn
por: Unuofin, Jeremiah Oshiomame, et al.
Publicado: (2018)

GC-MS Metabolic Profile and α-Glucosidase-, α-Amylase-, Lipase-, and Acetylcholinesterase-Inhibitory Activities of Eight Peach Varieties
por: Mihaylova, Dasha, et al.
Publicado: (2021)

In Vitro α-Amylase and α-Glucosidase Inhibitory and Antioxidant Activities of the Crude Extract and Solvent Fractions of Hagenia abyssinica Leaves
por: Kifle, Zemene Demelash, et al.
Publicado: (2021)

Phenolic compounds, antioxidant capacity, and α‐amylase and α‐glucosidase inhibitory activity of ethanol extracts of perilla seed meal
por: Choi, Ga‐Young, et al.
Publicado: (2023)

Design, Synthesis, In Silico Testing, and In Vitro Evaluation of Thiazolidinone-Based Benzothiazole Derivatives as Inhibitors of α-Amylase and α-Glucosidase
por: Khan, Shoaib, et al.
Publicado: (2022)

Inhibitory Potential of α-Amylase, α-Glucosidase, and Pancreatic Lipase by a Formulation of Five Plant Extracts: TOTUM-63
por: Haguet, Quentin, et al.
Publicado: (2023)

Antioxidant, Xanthine Oxidase, α-Amylase and α-Glucosidase Inhibitory Activities of Bioactive Compounds from Rumex crispus L. Root
por: Minh, Truong Ngoc, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_r3ql908bhh4bc9v914bee2ke25