Therapeutic Targeting of CDK7 Suppresses Tumor Progression in Intrahepatic Cholangiocarcinoma

Intrahepatic cholangiocarcinoma (ICC) is a lethal malignancy with high mortality and lack of effective therapeutic targets. Here, we found that expression of cyclin-dependent kinase 7 (CDK7) was significantly associated with higher tumor grade and worse prognosis in 96 ICC specimens. Depletion of CD...

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Detalles Bibliográficos
Autores principales: Chen, Hua-Dong, Huang, Chen-Song, Xu, Qiong-Cong, Li, Fuxi, Huang, Xi-Tai, Wang, Jie-Qin, Li, Shi-Jin, Zhao, Wei, Yin, Xiao-Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2020
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7053328/
https://www.ncbi.nlm.nih.gov/pubmed/32174795
http://dx.doi.org/10.7150/ijbs.39779

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