Cargando…

The Effects of Obesity on Outcome in Preclinical Animal Models of Infection and Sepsis: A Systematic Review and Meta-Analysis

BACKGROUND: Clinical studies suggest obesity paradoxically increases survival during bacterial infection and sepsis but decreases it with influenza, but these studies are observational. By contrast, animal studies of obesity in infection can prospectively compare obese versus nonobese controls. We p...

Descripción completa

Detalles Bibliográficos
Autores principales:	Xu, Wanying, Pepper, Dominique, Sun, Junfeng, Welsh, Judith, Cui, Xizhong, Eichacker, Peter Q.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2020
Materias:	Review Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7053456/ https://www.ncbi.nlm.nih.gov/pubmed/32211204 http://dx.doi.org/10.1155/2020/1508764

Ejemplares similares

Increased body mass index and adjusted mortality in ICU patients with sepsis or septic shock: a systematic review and meta-analysis
por: Pepper, Dominique J., et al.
Publicado: (2016)

A systematic review and meta-analysis of preclinical trials testing anti-toxin therapies for B. anthracis infection: A need for more robust study designs and results
por: Xu, Wanying, et al.
Publicado: (2017)

Correction: A systematic review and meta-analysis of preclinical trials testing anti-toxin therapies for B. anthracis infection: A need for more robust study designs and results
por: Xu, Wanying, et al.
Publicado: (2017)

Checkpoint inhibitor therapy in preclinical sepsis models: a systematic review and meta-analysis
por: Busch, Lindsay M., et al.
Publicado: (2020)

Effect of low-to-moderate hyperoxia on lung injury in preclinical animal models: a systematic review and meta-analysis
por: Minkove, Samuel, et al.
Publicado: (2023)

Growing insights into the potential benefits and risks of activated protein C administration in sepsis: a review of preclinical and clinical studies
por: Altaweel, Laith, et al.
Publicado: (2009)

Comprehensive adjusted outcome data are needed to assess the impact of immune checkpoint inhibitors in cancer patients with COVID‐19: Results of a systematic review and meta‐analysis
por: Minkove, Samuel J., et al.
Publicado: (2022)

The Potential Pathogenic Contributions of Endothelial Barrier and Arterial Contractile Dysfunction to Shock Due to B. anthracis Lethal and Edema Toxins
por: Suffredini, Dante A., et al.
Publicado: (2017)

A Review of the Efficacy of FDA-Approved B. anthracis Anti-Toxin Agents When Combined with Antibiotic or Hemodynamic Support in Infection- or Toxin-Challenged Preclinical Models
por: Couse, Zoe, et al.
Publicado: (2021)

Hydrocortisone decreases lethality and inflammatory cytokine and nitric oxide production in rats challenged with B. anthracis cell wall peptidoglycan
por: Li, Yan, et al.
Publicado: (2020)

Does Bacillus anthracis Lethal Toxin Directly Depress Myocardial Function? A Review of Clinical Cases and Preclinical Studies
por: Suffredini, Dante A., et al.
Publicado: (2015)

Comparison of survivors and nonsurvivors in 27 confirmed injectional anthrax cases from the 2009 outbreak in Scotland
por: Booth, M, et al.
Publicado: (2013)

Impact of Procalcitonin (PCT)-Guided Antibiotic Therapy on Mortality in Critically Ill Patients: A Systematic Review and Meta-Analysis of 18 Randomized Controlled Trials
por: Pepper, Dominique, et al.
Publicado: (2017)

B. anthracis associated cardiovascular dysfunction and shock: the potential contribution of both non-toxin and toxin components
por: Remy, Kenneth E, et al.
Publicado: (2013)

The Potential Contributions of Lethal and Edema Toxins to the Pathogenesis of Anthrax Associated Shock
por: Hicks, Caitlin W., et al.
Publicado: (2011)

Raxibacumab augments hemodynamic support and improves outcomes during shock with B. anthracis edema toxin alone or together with lethal toxin in canines
por: Remy, Kenneth E, et al.
Publicado: (2015)

Anthrax immune globulin improves hemodynamics and survival during B. anthracis toxin-induced shock in canines receiving titrated fluid and vasopressor support
por: Suffredini, Dante A., et al.
Publicado: (2017)

Sex-based analysis of treatment responses in animal models of sepsis: a preclinical systematic review protocol
por: Zhang, MengQi, et al.
Publicado: (2023)

Purified cell wall from the probiotic bacterium Lactobacillus gasseri activates systemic inflammation and, at higher doses, produces lethality in a rat model
por: Xu, Xinhui, et al.
Publicado: (2014)

Confirmed Bacillus anthracis Infection among Persons Who Inject Drugs, Scotland, 2009–2010
por: Booth, Malcolm, et al.
Publicado: (2014)

Protective properties of extracellular vesicles in sepsis models: a systematic review and meta-analysis of preclinical studies
por: Yang, Shujun, et al.
Publicado: (2023)

Analysis of Anthrax Immune Globulin Intravenous with Antimicrobial Treatment in Injection Drug Users, Scotland, 2009–2010
por: Cui, Xizhong, et al.
Publicado: (2017)

Efficacy and safety of regenerative cell therapy for pulmonary arterial hypertension in animal models: a preclinical systematic review protocol
por: Suen, Colin M., et al.
Publicado: (2016)

Effectiveness and mechanism of metformin in animal models of pulmonary fibrosis: A preclinical systematic review and meta-analysis
por: Wu, Xuanyu, et al.
Publicado: (2022)

Effect of acupuncture on neuroinflammation in animal models of Alzheimer’s disease: A preclinical systematic review and meta-analysis
por: Wu, Zhi-Guo, et al.
Publicado: (2023)

The Heart Is an Early Target of Anthrax Lethal Toxin in Mice: A Protective Role for Neuronal Nitric Oxide Synthase (nNOS)
por: Moayeri, Mahtab, et al.
Publicado: (2009)

Effects of hypercapnia in sepsis: protocol for a systematic review of clinical and preclinical data
por: Clyde, Thomas P., et al.
Publicado: (2018)

Impact of obesity on outcomes in patients with sepsis
por: Dobesh, PP, et al.
Publicado: (2014)

National Preclinical Sepsis Platform: developing a framework for accelerating innovation in Canadian sepsis research
por: Mendelson, Asher A., et al.
Publicado: (2021)

Preclinical animal models of COPD
por: Vlahos, Ross
Publicado: (2013)

Efficacy of mesenchymal stem cell therapy for sepsis: a meta-analysis of preclinical studies
por: Sun, Xue-Yi, et al.
Publicado: (2020)

Preclinical Evidence and Mechanism of Xingnaojing Injection for Cerebral Ischemia: A Systematic Review and Meta-Analysis of Animal Studies
por: Ma, Rong, et al.
Publicado: (2018)

Astragaloside IV Exerts Cardioprotection in Animal Models of Viral Myocarditis: A Preclinical Systematic Review and Meta-Analysis
por: Zhuang, Zhuang, et al.
Publicado: (2019)

The effects of cell therapy on seizures in animal models of epilepsy: protocol for systematic review and meta-analysis of preclinical studies
por: Dvir, Naomi, et al.
Publicado: (2019)

Gut microbiota changes in animal models of spinal cord injury: a preclinical systematic review and meta-analysis
por: Zhang, Zhenye, et al.
Publicado: (2023)

Protective effects and mechanism of curcumin in animal models of pulmonary fibrosis: a preclinical systematic review and meta-analysis
por: Hanyu, Fang, et al.
Publicado: (2023)

The impact of RAGE inhibition in animal models of bacterial sepsis: a systematic review and meta-analysis
por: Zhao, Xin, et al.
Publicado: (2017)

Early preclinical detection of prions in the skin of prion-infected animals
por: Wang, Zerui, et al.
Publicado: (2019)

The Usefulness of Systematic Reviews of Animal Experiments for the Design of Preclinical and Clinical Studies
por: de Vries, Rob B. M., et al.
Publicado: (2014)

Diabetes and Sepsis: Preclinical Findings and Clinical Relevance
por: Schuetz, Philipp, et al.
Publicado: (2011)

Cannot write session to /tmp/vufind_sessions/sess_kbd5e6997m2or70rtn9ntcdd5p