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S100A9 Increases IL-6 and RANKL Expressions through MAPKs and STAT3 Signaling Pathways in Osteocyte-Like Cells

OBJECTIVE: Calprotectin is a heterocomplex of S100A8 and S100A9 and is mainly secreted from neutrophils, monocytes, and chondrocytes in inflammatory condition. Calprotectin binds to RAGE and TLR4 and induces the expression of proinflammatory chemokines and cytokines in various cells. Periodontitis i...

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Detalles Bibliográficos
Autores principales:	Takagi, Ryosuke, Sakamoto, Eijiro, Kido, Jun-ichi, Inagaki, Yuji, Hiroshima, Yuka, Naruishi, Koji, Yumoto, Hiromichi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7053464/ https://www.ncbi.nlm.nih.gov/pubmed/32149126 http://dx.doi.org/10.1155/2020/7149408

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