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Plasma ubiquitin C-terminal hydrolase L1 levels reflect disease stage and motor severity in Parkinson’s disease

Parkinson’s disease (PD) is characterized by Lewy bodies containing α-synuclein and ubiquitin aggregates, their co-occurrence possibly linked to a failure of the ubiquitin proteasome system. Ubiquitin C-terminal hydrolase L1 (UCHL1) plays an important role in maintenance of nervous system integrity,...

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Detalles Bibliográficos
Autores principales: Ng, Adeline Su Lyn, Tan, Yi Jayne, Lu, Zhonghao, Ng, Ebonne Yulin, Ng, Samuel Yong Ern, Chia, Nicole Shuang Yu, Setiawan, Fiona, Xu, Zheyu, Keong, Nicole Chwee Har, Tay, Kay Yaw, Au, Wing Lok, Tan, Louis Chew Seng, Tan, Eng-King
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7053593/
https://www.ncbi.nlm.nih.gov/pubmed/31932518
http://dx.doi.org/10.18632/aging.102695