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Plasma ubiquitin C-terminal hydrolase L1 levels reflect disease stage and motor severity in Parkinson’s disease
Parkinson’s disease (PD) is characterized by Lewy bodies containing α-synuclein and ubiquitin aggregates, their co-occurrence possibly linked to a failure of the ubiquitin proteasome system. Ubiquitin C-terminal hydrolase L1 (UCHL1) plays an important role in maintenance of nervous system integrity,...
Autores principales: | Ng, Adeline Su Lyn, Tan, Yi Jayne, Lu, Zhonghao, Ng, Ebonne Yulin, Ng, Samuel Yong Ern, Chia, Nicole Shuang Yu, Setiawan, Fiona, Xu, Zheyu, Keong, Nicole Chwee Har, Tay, Kay Yaw, Au, Wing Lok, Tan, Louis Chew Seng, Tan, Eng-King |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7053593/ https://www.ncbi.nlm.nih.gov/pubmed/31932518 http://dx.doi.org/10.18632/aging.102695 |
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