Cargando…

MTDH promotes metastasis of clear cell renal cell carcinoma by activating SND1-mediated ERK signaling and epithelial-mesenchymal transition

Background: Metastasis is the principal cause of renal cell carcinoma-associated mortality. Metadherin (MTDH) was identified as a vital metastasis driver involved in the metastatic progression of various types of tumors, suggesting that MTDH is a prognostic metastatic biomarker and potential therape...

Descripción completa

Detalles Bibliográficos
Autores principales:	He, Anbang, He, Shiming, Huang, Cong, Chen, Zhicong, Wu, Yucai, Gong, Yanqing, Li, Xuesong, Zhou, Liqun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals 2020
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7053596/ https://www.ncbi.nlm.nih.gov/pubmed/31978894 http://dx.doi.org/10.18632/aging.102694

Ejemplares similares

TGF-β-induced transgelin promotes bladder cancer metastasis by regulating epithelial-mesenchymal transition and invadopodia formation
por: Chen, Zhicong, et al.
Publicado: (2019)

Small Molecule Inhibitors that Disrupt the MTDH-SND1 Complex Suppress Breast Cancer Progression and Metastasis
por: Shen, Minhong, et al.
Publicado: (2022)

Long non-coding RNA DANCR promotes malignant phenotypes of bladder cancer cells by modulating the miR-149/MSI2 axis as a ceRNA
por: Zhan, Yonghao, et al.
Publicado: (2018)

Correction: Long non-coding RNA DANCR promotes malignant phenotypes of bladder cancer cells by modulating the miR-149/MSI2 axis as a ceRNA
por: Zhan, Yonghao, et al.
Publicado: (2023)

Identification of immune-related LncRNA for predicting prognosis and immunotherapeutic response in bladder cancer
por: Wu, Yucai, et al.
Publicado: (2020)

P4HB: A novel diagnostic and prognostic biomarker for bladder carcinoma
por: Wu, Yucai, et al.
Publicado: (2021)

Prognostic value of long non-coding RNA signatures in bladder cancer
por: He, Anbang, et al.
Publicado: (2019)

Long non-coding RNA SOX2OT promotes the stemness phenotype of bladder cancer cells by modulating SOX2
por: Zhan, Yonghao, et al.
Publicado: (2020)

Correction: Long non-coding RNA SOX2OT promotes the stemness phenotype of bladder cancer cells by modulating SOX2
por: Zhan, Yonghao, et al.
Publicado: (2023)

Long non-coding RNA HNF1A-AS1 promotes proliferation and suppresses apoptosis of bladder cancer cells through upregulating Bcl-2
por: Zhan, Yonghao, et al.
Publicado: (2017)

Identification of the Six-RNA-Binding Protein Signature for Prognosis Prediction in Bladder Cancer
por: Wu, Yucai, et al.
Publicado: (2020)

ZFAS1: A novel vital oncogenic lncRNA in multiple human cancers
por: He, Anbang, et al.
Publicado: (2018)

Comprehensive bioinformatics analyses of APOBECs family and identification of APOBEC3D as the unfavorable prognostic biomarker in clear cell renal cell carcinoma
por: Zhu, Zhenpeng, et al.
Publicado: (2021)

Pharmacological Disruption of the MTDH-SND1 Complex Enhances Tumor Antigen Presentation and Synergizes with Anti-PD-1 Therapy in Metastatic Breast Cancer
por: Shen, Minhong, et al.
Publicado: (2022)

Increased expression of long non-coding RNA CCEPR is associated with poor prognosis and promotes tumorigenesis in urothelial bladder carcinoma
por: Zhan, Yonghao, et al.
Publicado: (2017)

Correction: Increased expression of long non-coding RNA CCEPR is associated with poor prognosis and promotes tumorigenesis in urothelial bladder carcinoma
por: Zhan, Yonghao, et al.
Publicado: (2023)

Downregulation of CLDN7 due to promoter hypermethylation is associated with human clear cell renal cell carcinoma progression and poor prognosis
por: Li, Yifan, et al.
Publicado: (2018)

Downregulation of PARVA promotes metastasis by modulating integrin-linked kinase activity and regulating MAPK/ERK and MLC2 signaling in prostate cancer
por: Huang, Cong, et al.
Publicado: (2021)

SND@LHC
por: Ahdida, C., et al.
Publicado: (2020)

Using microRNAs as Novel Predictors of Urologic Cancer Survival: An Integrated Analysis
por: Chen, Zhicong, et al.
Publicado: (2018)

High aspartate transaminase/alanine transaminase ratio predicts poor prognosis in patients with localized upper tract urothelial cancer: a propensity score-matched study in a large Chinese center
por: Li, Yifan, et al.
Publicado: (2019)

Ascorbic acid induced TET2 enzyme activation enhances cancer immunotherapy efficacy in renal cell carcinoma
por: Peng, Ding, et al.
Publicado: (2022)

Upregulation of ATP Binding Cassette Subfamily C Member 5 facilitates Prostate Cancer progression and Enzalutamide resistance via the CDK1-mediated AR Ser81 Phosphorylation Pathway
por: Ji, Guangjie, et al.
Publicado: (2021)

Cytoskeleton regulator RNA expression on cancer-associated fibroblasts is associated with prognosis and immunotherapy response in bladder cancer
por: Wu, Yucai, et al.
Publicado: (2023)

AEG-1/MTDH-activated autophagy enhances human malignant glioma susceptibility to TGF-β1-triggered epithelial-mesenchymal transition
por: Zou, Meijuan, et al.
Publicado: (2016)

SND Upgrade Status
por: Abramov, G N, et al.
Publicado: (2004)

[Retracted] MicroRNA‑154 inhibits the growth and metastasis of gastric cancer cells by directly targeting MTDH
por: Qiao, Wenhui, et al.
Publicado: (2023)

Comprehensive analysis of m6A regulators prognostic value in prostate cancer
por: Ji, Guangjie, et al.
Publicado: (2020)

CCSP SND quick reference
por: Carroll, Brandon
Publicado: (2007)

AB179. KCNJ1 inhibits tumor proliferation and metastasis and is a prognostic factor in clear cell renal cell carcinoma
por: Guo, Zhongqiang, et al.
Publicado: (2014)

Multiparametric Magnetic Resonance Imaging-based Prostate Specific Antigen Density and PI-RADSv2 score help identify Apical Prostate Cancer
por: Huang, Cong, et al.
Publicado: (2023)

miR-145 and miR-497 suppress TGF-β-induced epithelial–mesenchymal transition of non-small cell lung cancer by targeting MTDH
por: Yin, Qi, et al.
Publicado: (2018)

N-Glycosylation on Asn50 of SND1 Is Required for Glioma U87 Cell Proliferation and Metastasis
por: Zhou, Ying, et al.
Publicado: (2022)

Identification of a claudin-low subtype in clear cell renal cell carcinoma with implications for the evaluation of clinical outcomes and treatment efficacy
por: Zhang, Cuijian, et al.
Publicado: (2022)

MTDH genetic variants in colorectal cancer patients
por: Gnosa, Sebastian, et al.
Publicado: (2016)

Increased phosphorylated CREB1 protein correlates with poor prognosis in clear cell renal cell carcinoma
por: Zhang, Zhongyuan, et al.
Publicado: (2021)

Emulsion Reconstruction Analysis in SND@LHC
por: Krishnan, Tanvi
Publicado: (2023)

Answers to referees on SND@LHC TP
por: Ahdida, C, et al.
Publicado: (2021)

Status of the FASER and SND@LHC experiments
por: Li, Ke
Publicado: (2022)

Searches for new physics at SND@LHC
por: Boyarsky, Alexey, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_h0bhv52v5oules6g076vhfem19