Chikusetsu saponin IVa protects pancreatic β cell against intermittent high glucose-induced injury by activating Wnt/β-catenin/TCF7L2 pathway

Islet β cell mass reduction induced by glucose fluctuation is crucial for the development and progression of T2DM. Chikusetsu saponin IVa (CHS) had protective effects against DM and related injuries. Here we aimed to investigate the role of CHS in β cell injuries and its possible mechanism involved....

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Detalles Bibliográficos
Autores principales: Cui, Jia, Duan, Jialin, Chu, Jianjie, Guo, Chao, Xi, Miaomiao, Li, Yi, Weng, Yan, Wei, Guo, Yin, Ying, Wen, Aidong, Qiao, Boling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2020
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7053639/
https://www.ncbi.nlm.nih.gov/pubmed/31969494
http://dx.doi.org/10.18632/aging.102702

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7053639/
https://www.ncbi.nlm.nih.gov/pubmed/31969494
http://dx.doi.org/10.18632/aging.102702

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