Cargando…

Araloside C attenuates atherosclerosis by modulating macrophage polarization via Sirt1-mediated autophagy

Atherosclerosis-related cardiovascular disease is still the predominant cause of death worldwide. Araloside C (AsC), a natural saponin, exerts extensive anti-inflammatory properties. In this study, we explored the protective effects and mechanism of AsC on macrophage polarization in atherosclerosis...

Descripción completa

Detalles Bibliográficos
Autores principales:	Luo, Yun, Lu, Shan, Gao, Ye, Yang, Ke, Wu, Daoshun, Xu, Xudong, Sun, Guibo, Sun, Xiaobo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals 2020
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7053643/ https://www.ncbi.nlm.nih.gov/pubmed/31986489 http://dx.doi.org/10.18632/aging.102708

Ejemplares similares

Araloside C Prevents Hypoxia/Reoxygenation-Induced Endoplasmic Reticulum Stress via Increasing Heat Shock Protein 90 in H9c2 Cardiomyocytes
por: Du, Yuyang, et al.
Publicado: (2018)

Ginsenoside Compound K Attenuates Ox-LDL-Mediated Macrophage Inflammation and Foam Cell Formation via Autophagy Induction and Modulating NF-κB, p38, and JNK MAPK Signaling
por: Lu, Shan, et al.
Publicado: (2020)

Isorhamnetin Attenuates Atherosclerosis by Inhibiting Macrophage Apoptosis via PI3K/AKT Activation and HO-1 Induction
por: Luo, Yun, et al.
Publicado: (2015)

Iminostilbene, a novel small-molecule modulator of PKM2, suppresses macrophage inflammation in myocardial ischemia–reperfusion injury
por: Lu, Shan, et al.
Publicado: (2020)

Rapamycin and FTY720 Alleviate Atherosclerosis by Cross Talk of Macrophage Polarization and Autophagy
por: Sun, Rui-zhen, et al.
Publicado: (2018)

Gastroprotective effects of Kangfuxin against water-immersion and restraint stress-induced gastric ulcer in rats: roles of antioxidation, anti-inflammation, and pro-survival
por: Lu, Shan, et al.
Publicado: (2019)

Macrophage Polarization in Atherosclerosis
por: Eshghjoo, Sahar, et al.
Publicado: (2022)

Saponins in Chinese Herbal Medicine Exerts Protection in Myocardial Ischemia–Reperfusion Injury: Possible Mechanism and Target Analysis
por: Wang, Ruiying, et al.
Publicado: (2021)

Mechanism overview and target mining of atherosclerosis: Endothelial cell injury in atherosclerosis is regulated by glycolysis (Review)
por: Wang, Ruiying, et al.
Publicado: (2021)

Protective effects of Araloside C against myocardial ischaemia/reperfusion injury: potential involvement of heat shock protein 90
por: Wang, Min, et al.
Publicado: (2017)

Inhibitory Effects of Ginsenoside Rb1 on Early Atherosclerosis in ApoE-/- Mice via Inhibition of Apoptosis and Enhancing Autophagy
por: Zhou, Ping, et al.
Publicado: (2018)

Macrophage polarization states in atherosclerosis
por: Wu, Jiayong, et al.
Publicado: (2023)

Macrophage polarization and metabolism in atherosclerosis
por: Hou, Pengbo, et al.
Publicado: (2023)

Macrophage-specific autophagy-related gene HSPB8 is involved in the macrophage polarization in atherosclerosis
por: Wang, Juping, et al.
Publicado: (2023)

Ginsenoside F1 Ameliorates Endothelial Cell Inflammatory Injury and Prevents Atherosclerosis in Mice through A20-Mediated Suppression of NF-kB Signaling
por: Qin, Meng, et al.
Publicado: (2017)

Gypenoside XVII Prevents Atherosclerosis by Attenuating Endothelial Apoptosis and Oxidative Stress: Insight into the ERα-Mediated PI3K/Akt Pathway
por: Yang, Ke, et al.
Publicado: (2017)

Macrophage Autophagy in Atherosclerosis
por: Maiuri, Maria Chiara, et al.
Publicado: (2013)

SIRT2 Deficiency Modulates Macrophage Polarization and Susceptibility to Experimental Colitis
por: Lo Sasso, Giuseppe, et al.
Publicado: (2014)

SIRT1 inhibition promotes atherosclerosis through impaired autophagy
por: Yang, Xiaofeng, et al.
Publicado: (2017)

Attenuation of TNF-α-Induced Inflammatory Injury in Endothelial Cells by Ginsenoside Rb1 via Inhibiting NF-κB, JNK and p38 Signaling Pathways
por: Zhou, Ping, et al.
Publicado: (2017)

Dihydromyricetin Inhibits M1 Macrophage Polarization in Atherosclerosis by Modulating miR-9-Mediated SIRT1/NF-κB Signaling Pathway
por: Yang, Zhousheng, et al.
Publicado: (2023)

Loganin inhibits macrophage M1 polarization and modulates sirt1/NF-κB signaling pathway to attenuate ulcerative colitis
por: Liu, Shi, et al.
Publicado: (2020)

Macrophage autophagy in macrophage polarization, chronic inflammation and organ fibrosis
por: Wen, Jun-Hao, et al.
Publicado: (2022)

Hypertrophic Preconditioning Attenuates Myocardial Ischaemia‐Reperfusion Injury by Modulating SIRT3‐SOD2‐mROS‐Dependent Autophagy
por: Ma, Lei‐Lei, et al.
Publicado: (2021)

Daeshiho-tang Attenuates Atherosclerosis by Regulating Cholesterol Metabolism and Inducing M2 Macrophage Polarization
por: Song, Min-Young, et al.
Publicado: (2022)

Akt Signaling in Macrophage Polarization, Survival, and Atherosclerosis
por: Linton, MacRae F., et al.
Publicado: (2019)

The role of Sirt6 in osteoarthritis and its effect on macrophage polarization
por: Chen, Jinwei, et al.
Publicado: (2022)

Deficiency of LMP10 Attenuates Diet-Induced Atherosclerosis by Inhibiting Macrophage Polarization and Inflammation in Apolipoprotein E Deficient Mice
por: Liao, Jiawei, et al.
Publicado: (2020)

Human amnion mesenchymal stem cells attenuate atherosclerosis by modulating macrophage function to reduce immune response
por: Wei, Xiufang, et al.
Publicado: (2019)

Weak UVB Irradiation Promotes Macrophage M2 Polarization and Stabilizes Atherosclerosis
por: Li, Xin-Yun, et al.
Publicado: (2021)

β-Sitosterol modulates macrophage polarization and attenuates rheumatoid inflammation in mice
por: Liu, Rui, et al.
Publicado: (2019)

Liraglutide Attenuates Hepatic Ischemia–Reperfusion Injury by Modulating Macrophage Polarization
por: Li, Shang-Lin, et al.
Publicado: (2022)

Molecular Pathways Regulating Macrophage Polarization: Implications for Atherosclerosis
por: Hoeksema, Marten A., et al.
Publicado: (2012)

Macrophage Polarization in the Perivascular Fat Was Associated With Coronary Atherosclerosis
por: Farias‐Itao, Daniela Souza, et al.
Publicado: (2022)

Berberine-induced TFEB deacetylation by SIRT1 promotes autophagy in peritoneal macrophages
por: Zheng, Yinghong, et al.
Publicado: (2021)

Synergistic Antioxidant Effects of Araloside A and L-Ascorbic Acid on H(2)O(2)-Induced HEK293 Cells: Regulation of Cellular Antioxidant Status
por: Tian, Yaqin, et al.
Publicado: (2021)

Prostaglandin E(3) attenuates macrophage‐associated inflammation and prostate tumour growth by modulating polarization
por: Cui, Jing, et al.
Publicado: (2021)

Ginsenoside compound K protects human umbilical vein endothelial cells against oxidized low-density lipoprotein-induced injury via inhibition of nuclear factor-κB, p38, and JNK MAPK pathways
por: Lu, Shan, et al.
Publicado: (2019)

Aminooxyacetic acid attenuates post‐infarct cardiac dysfunction by balancing macrophage polarization through modulating macrophage metabolism in mice
por: Zhao, Pei, et al.
Publicado: (2020)

SIRT3 attenuates coronary atherosclerosis in diabetic patients by regulating endothelial cell function
por: Gong, Huiping, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_q7f2o459hvusi819163ogiohmq