Cargando…

Distinct gene expression patterns in vector-residing Leishmania infantum identify parasite stage-enriched markers

BACKGROUND: Leishmaniasis is a vector-borne neglected disease. Inside the natural sand fly vector, the promastigote forms of Leishmania undergo a series of extracellular developmental stages to reach the infectious stage, the metacyclic promastigote. There is limited information regarding the expres...

Descripción completa

Detalles Bibliográficos
Autores principales:	Coutinho-Abreu, Iliano V., Serafim, Tiago D., Meneses, Claudio, Kamhawi, Shaden, Oliveira, Fabiano, Valenzuela, Jesus G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7053709/ https://www.ncbi.nlm.nih.gov/pubmed/32126078 http://dx.doi.org/10.1371/journal.pntd.0008014

Ejemplares similares

Sequential blood meals augment vector infectiousness by promoting Leishmania replication and triggering amplification of metacyclics via a novel retroleptomonad developmental stage
por: Serafim, Tiago D., et al.
Publicado: (2018)

Leishmania infection induces a limited differential gene expression in the sand fly midgut
por: Coutinho-Abreu, Iliano V., et al.
Publicado: (2020)

Binding of Leishmania infantum Lipophosphoglycan to the Midgut Is Not Sufficient To Define Vector Competence in Lutzomyia longipalpis Sand Flies
por: Coutinho-Abreu, Iliano V., et al.
Publicado: (2020)

The Gut Microbiome of the Vector Lutzomyia longipalpis Is Essential for Survival of Leishmania infantum
por: Kelly, Patrick H., et al.
Publicado: (2017)

New Insights Into the Transmissibility of Leishmania infantum From Dogs to Sand Flies: Experimental Vector-Transmission Reveals Persistent Parasite Depots at Bite Sites
por: Aslan, Hamide, et al.
Publicado: (2016)

Impaired development of a miltefosine-resistant Leishmania infantum strain in the sand fly vectors Phlebotomus perniciosus and Lutzomyia longipalpis
por: Van Bockstal, Lieselotte, et al.
Publicado: (2019)

Incrimination of Phlebotomus kandelakii and Phlebotomus balcanicus as Vectors of Leishmania infantum in Tbilisi, Georgia
por: Giorgobiani, Ekaterina, et al.
Publicado: (2012)

Immunity to Sand Fly Salivary Protein LJM11 Modulates Host Response to Vector-Transmitted Leishmania Conferring Ulcer-Free Protection
por: Gomes, Regis, et al.
Publicado: (2012)

Intradermal Immunization of Leishmania donovani Centrin Knock-Out Parasites in Combination with Salivary Protein LJM19 from Sand Fly Vector Induces a Durable Protective Immune Response in Hamsters
por: Fiuza, Jacqueline Araújo, et al.
Publicado: (2016)

Immunity to Distinct Sand Fly Salivary Proteins Primes the Anti-Leishmania Immune Response towards Protection or Exacerbation of Disease
por: Oliveira, Fabiano, et al.
Publicado: (2008)

Engineering a vector-based pan-Leishmania vaccine for humans: proof of principle
por: Cecílio, Pedro, et al.
Publicado: (2020)

Characterization of the Early Inflammatory Infiltrate at the Feeding Site of Infected Sand Flies in Mice Protected from Vector-Transmitted Leishmania major by Exposure to Uninfected Bites
por: Teixeira, Clarissa, et al.
Publicado: (2014)

Discovery of Markers of Exposure Specific to Bites of Lutzomyia longipalpis, the Vector of Leishmania infantum chagasi in Latin America
por: Teixeira, Clarissa, et al.
Publicado: (2010)

Leishmania infantum xenodiagnosis from vertically infected dogs reveals significant skin tropism
por: Scorza, Breanna M., et al.
Publicado: (2021)

Molecular Diversity between Salivary Proteins from New World and Old World Sand Flies with Emphasis on Bichromomyia olmeca, the Sand Fly Vector of Leishmania mexicana in Mesoamerica
por: Abdeladhim, Maha, et al.
Publicado: (2016)

KSAC, a Defined Leishmania Antigen, plus Adjuvant Protects against the Virulence of L. major Transmitted by Its Natural Vector Phlebotomus duboscqi
por: Gomes, Regis, et al.
Publicado: (2012)

A second generation leishmanization vaccine with a markerless attenuated Leishmania major strain using CRISPR gene editing
por: Zhang, Wen-Wei, et al.
Publicado: (2020)

Identification of adipocytes as target cells for Leishmania infantum parasites
por: Schwing, Aurélie, et al.
Publicado: (2021)

Vector Transmission of Leishmania Abrogates Vaccine-Induced Protective Immunity
por: Peters, Nathan C., et al.
Publicado: (2009)

Comparative Evolution of Sand Fly Salivary Protein Families and Implications for Biomarkers of Vector Exposure and Salivary Vaccine Candidates
por: Coutinho-Abreu, Iliano V., et al.
Publicado: (2018)

Leishmania major-Infected Phlebotomus duboscqi Sand Fly Bites Enhance Mast Cell Degranulation
por: Sánchez-García, Laura, et al.
Publicado: (2023)

Characterization of Phlebotomus papatasi Peritrophins, and the Role of PpPer1 in Leishmania major Survival in its Natural Vector
por: Coutinho-Abreu, Iliano V., et al.
Publicado: (2013)

Thiophene derivatives activity against the protozoan parasite Leishmania infantum
por: Bigot, Sophia, et al.
Publicado: (2022)

Impact of insecticide-treated bednets and indoor residual spraying in controlling populations of Phlebotomus duboscqi, the vector of Leishmania major in Central Mali
por: Coulibaly, Cheick Amadou, et al.
Publicado: (2018)

Vector Saliva in Vaccines for Visceral Leishmaniasis: A Brief Encounter of High Consequence?
por: Kamhawi, Shaden, et al.
Publicado: (2014)

Lutzomyia migonei is a permissive vector competent for Leishmania infantum
por: Guimarães, Vanessa Cristina Fitipaldi Veloso, et al.
Publicado: (2016)

Towards a Sustainable Vector-Control Strategy in the Post Kala-Azar Elimination Era
por: Garlapati, Rajesh, et al.
Publicado: (2021)

Targeting the Midgut Secreted PpChit1 Reduces Leishmania major Development in Its Natural Vector, the Sand Fly Phlebotomus papatasi
por: Coutinho-Abreu, Iliano V., et al.
Publicado: (2010)

Leishmania infantum Asparagine Synthetase A Is Dispensable for Parasites Survival and Infectivity
por: Faria, Joana, et al.
Publicado: (2016)

Toward a Defined Anti-Leishmania Vaccine Targeting Vector Antigens: Characterization of a Protective Salivary Protein
por: Valenzuela, Jesus G., et al.
Publicado: (2001)

Centrin-deficient Leishmania mexicana confers protection against Old World visceral leishmaniasis
por: Karmakar, Subir, et al.
Publicado: (2022)

Liver infusion tryptose (LIT): the best choice for growth, viability, and infectivity of Leishmania infantum parasites
por: Costa, Ana Flávia Pereira, et al.
Publicado: (2020)

Enhanced Protective Efficacy of Nonpathogenic Recombinant Leishmania tarentolae Expressing Cysteine Proteinases Combined with a Sand Fly Salivary Antigen
por: Zahedifard, Farnaz, et al.
Publicado: (2014)

Development of a Natural Model of Cutaneous Leishmaniasis: Powerful Effects of Vector Saliva and Saliva Preexposure on the Long-Term Outcome of Leishmania major Infection in the Mouse Ear Dermis
por: Belkaid, Yasmine, et al.
Publicado: (1998)

Leishmania infantum EndoG Is an Endo/Exo-Nuclease Essential for Parasite Survival
por: Rico, Eva, et al.
Publicado: (2014)

Detection of Leishmania infantum DNA in the non-parasitized lung of dogs with visceral leishmaniasis
por: Goncalves, Ricardo, et al.
Publicado: (2018)

Effect of Silica Based Nanoparticles against Plasmodium falciparum and Leishmania infantum parasites
por: Tsamesidis, Ioannis, et al.
Publicado: (2021)

Sand flies: Basic information on the vectors of leishmaniasis and their interactions with Leishmania parasites
por: Cecílio, Pedro, et al.
Publicado: (2022)

A cross-sectional study of the filarial and Leishmania co-endemicity in two ecologically distinct settings in Mali
por: Sangare, Moussa Brema, et al.
Publicado: (2018)

Serosurvey of anti-Leishmania (Leishmania) infantum antibodies in hunting dogs and hunters in Brazil
por: Kmetiuk, Louise Bach, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_n1nf8fn91ce6911vb51bccjkb4