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Mathematical modeling and parameter estimation of levodopa motor response in patients with parkinson disease

Parkinson disease (PD) is characterized by a clear beneficial motor response to levodopa (LD) treatment. However, with disease progression and longer LD exposure, drug-related motor fluctuations usually occur. Recognition of the individual relationship between LD concentration and its effect may be...

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Detalles Bibliográficos
Autores principales:	Ursino, Mauro, Magosso, Elisa, Lopane, Giovanna, Calandra-Buonaura, Giovanna, Cortelli, Pietro, Contin, Manuela
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7053720/ https://www.ncbi.nlm.nih.gov/pubmed/32126124 http://dx.doi.org/10.1371/journal.pone.0229729

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