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Aptamer-Conjugated Gold Nanoparticles Targeting Epidermal Growth Factor Receptor Variant III for the Treatment of Glioblastoma

PURPOSE: In this study, we constructed novel brain-targeting complexes (U2-AuNP) by conjugating aptamer U2 to the gold nanoparticle (AuNPs) surface as a promising option for GBM therapy. MATERIALS AND METHODS: The properties of the U2-AuNP complexes were thoroughly characterized. Then, we detected t...

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Detalles Bibliográficos
Autores principales:	Peng, Li, Liang, Yanling, Zhong, Xinxin, Liang, Zhiman, Tian, Yinghong, Li, Shuji, Liang, Jingxue, Wang, Ransheng, Zhong, Yuqi, Shi, Yusheng, Zhang, Xingmei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2020
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7053811/ https://www.ncbi.nlm.nih.gov/pubmed/32184591 http://dx.doi.org/10.2147/IJN.S238206

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