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Hesperetin reverses P-glycoprotein-mediated cisplatin resistance in DDP-resistant human lung cancer cells via modulation of the nuclear factor-κB signaling pathway
Lung cancer is the leading cause of cancer-associated mortality worldwide. Cisplatin (DDP) is a first-line chemotherapeutic drug for the treatment of lung cancer; however, the majority of patients develop resistance to DDP. P-glycoprotein (P-gp), also referred to as multidrug resistance (MDR) protei...
Autores principales: | Kong, Wencui, Ling, Xiaoming, Chen, Ying, Wu, Xiaoli, Zhao, Zhongquan, Wang, Wenwu, Wang, Shuiliang, Lai, Guoxiang, Yu, Zongyang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7053858/ https://www.ncbi.nlm.nih.gov/pubmed/32124932 http://dx.doi.org/10.3892/ijmm.2020.4485 |
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