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HIF-1α attenuates neuronal apoptosis by upregulating EPO expression following cerebral ischemia-reperfusion injury in a rat MCAO model

Hypoxia-inducible factor-1α (HIF-1α) is a key transcriptional factor in response to hypoxia and is involved in ischemic stroke. In the present study, the potential for HIF-1α to inhibit neuronal apoptosis through upregulating erythropoietin (EPO) was investigated in a transient middle cerebral arter...

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Detalles Bibliográficos
Autores principales: Li, Jun, Tao, Tao, Xu, Jian, Liu, Zhi, Zou, Zhehua, Jin, Minglu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7053873/
https://www.ncbi.nlm.nih.gov/pubmed/32124933
http://dx.doi.org/10.3892/ijmm.2020.4480