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The ROCK isoforms differentially regulate the morphological characteristics of carcinoma cells
Rho-associated kinase (ROCK) activity drives cell migration via actomyosin contractility. During invasion, individual cancer cells can transition between 2 modes of migration, mesenchymal and amoeboid. Changes in ROCK activity can cause a switch between these migration phenotypes which are defined b...
Autores principales: | Jerrell, Rachel J., Leih, Mitchell J., Parekh, Aron |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7053931/ https://www.ncbi.nlm.nih.gov/pubmed/28650698 http://dx.doi.org/10.1080/21541248.2017.1341366 |
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