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Myosin V executes steps of variable length via structurally constrained diffusion

The molecular motor myosin V transports cargo by stepping on actin filaments, executing a random diffusive search for actin binding sites at each step. A recent experiment suggests that the joint between the myosin lever arms may not rotate freely, as assumed in earlier studies, but instead has a pr...

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Detalles Bibliográficos
Autores principales: Hathcock, David, Tehver, Riina, Hinczewski, Michael, Thirumalai, D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7054003/
https://www.ncbi.nlm.nih.gov/pubmed/31939739
http://dx.doi.org/10.7554/eLife.51569