Cargando…

A randomised controlled study of high intensity exercise as a dishabituating stimulus to improve hypoglycaemia awareness in people with type 1 diabetes: a proof-of-concept study

AIMS/HYPOTHESIS: Approximately 25% of people with type 1 diabetes have suppressed counterregulatory hormonal and symptomatic responses to insulin-induced hypoglycaemia, which renders them at increased risk of severe, disabling hypoglycaemia. This is called impaired awareness of hypoglycaemia (IAH),...

Descripción completa

Detalles Bibliográficos
Autores principales:	Farrell, Catriona M., McNeilly, Alison D., Fournier, Paul, Jones, Timothy, Hapca, Simona M., West, Daniel, McCrimmon, Rory J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Berlin Heidelberg 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7054230/ https://www.ncbi.nlm.nih.gov/pubmed/31942669 http://dx.doi.org/10.1007/s00125-019-05076-5

Ejemplares similares

Cold-induced dishabituation in rodents exposed to recurrent hypoglycaemia
por: Vickneson, Keeran, et al.
Publicado: (2021)

High‐intensity training as a novel treatment for impaired awareness of hypoglycaemia in type 1 diabetes [HIT4HYPOS]: Protocol for a randomized parallel‐group study
por: Farrell, Catriona M., et al.
Publicado: (2020)

Impaired hypoglycaemia awareness in type 1 diabetes: lessons from the lab
por: McNeilly, Alison D., et al.
Publicado: (2018)

Clinical approaches to treat impaired awareness of hypoglycaemia
por: Farrell, Catriona M., et al.
Publicado: (2021)

Real-time Continuous Glucose Monitoring During a Hyperinsulinemic-Hypoglycemic Clamp Significantly Underestimates the Degree of Hypoglycemia
por: Farrell, Catriona M., et al.
Publicado: (2020)

Consequences of recurrent hypoglycaemia on brain function in diabetes
por: McCrimmon, Rory J.
Publicado: (2021)

Remembrance of things past: The consequences of recurrent hypoglycaemia in diabetes
por: McCrimmon, Rory J.
Publicado: (2022)

The mechanism of dishabituation
por: Steiner, Genevieve Z., et al.
Publicado: (2014)

In-vivo correlations between skin metabolic oscillations and vasomotion in wild-type mice and in a model of oxidative stress
por: Smirni, Salvatore, et al.
Publicado: (2019)

Dishabituation of the BOLD response to speech sounds
por: Zevin, Jason D, et al.
Publicado: (2005)

Central deficiency of IL-6Ra in mice impairs glucose-stimulated insulin secretion
por: McNeilly, Alison D., et al.
Publicado: (2022)

Reducing Glut2 throughout the body does not result in cognitive behaviour differences in aged male mice
por: Morrice, Nicola, et al.
Publicado: (2020)

Glucose Sensing During Hypoglycemia: Lessons From the Lab
por: McCrimmon, Rory
Publicado: (2009)

Loss of O-GlcNAcase catalytic activity leads to defects in mouse embryogenesis
por: Muha, Villő, et al.
Publicado: (2021)

The suitability of patient-reported outcome measures used to assess the impact of hypoglycaemia on quality of life in people with diabetes: a systematic review using COSMIN methods
por: Carlton, Jill, et al.
Publicado: (2021)

Reducing the burden of hypoglycaemia in people with diabetes through increased understanding: design of the Hypoglycaemia REdefining SOLutions for better liVEs (Hypo‐RESOLVE) project
por: de Galan, B. E., et al.
Publicado: (2020)

Hypoglycaemia events with iGlarLixi versus premix biphasic insulin aspart 30 (BIAsp 30) in people with type 2 diabetes advancing from basal insulin: An analysis of the SoliMix trial
por: McCrimmon, Rory J., et al.
Publicado: (2022)

Hypo‐METRICS: Hypoglycaemia—MEasurement, ThResholds and ImpaCtS—A multi‐country clinical study to define the optimal threshold and duration of sensor‐detected hypoglycaemia that impact the experience of hypoglycaemia, quality of life and health economic outcomes: The study protocol
por: Divilly, Patrick, et al.
Publicado: (2022)

Hypoglycemia in Type 1 Diabetes
por: McCrimmon, Rory J., et al.
Publicado: (2010)

Habituation and Dishabituation in Motor Behavior: Experiment and Neural Dynamic Model
por: Aerdker, Sophie, et al.
Publicado: (2022)

SGLT inhibitor adjunct therapy in type 1 diabetes
por: McCrimmon, Rory J., et al.
Publicado: (2018)

The genetic association of the transcription factor NPAT with glycemic response to metformin involves regulation of fuel selection
por: Chen, Changwei, et al.
Publicado: (2021)

Auditory Stimulation Dishabituates Olfactory Responses via Noradrenergic Cortical Modulation
por: Smith, Jonathan J., et al.
Publicado: (2009)

Reaction-diffusion memory unit: Modeling of sensitization, habituation and dishabituation in the brain
por: Carnaghi, Matthew M., et al.
Publicado: (2019)

Use of a habituation–dishabituation test to determine canine olfactory sensitivity
por: Moser, Ariella Y., et al.
Publicado: (2022)

Glycaemic thresholds for counterregulatory hormone and symptom responses to hypoglycaemia in people with and without type 1 diabetes: a systematic review
por: Verhulst, Clementine E. M., et al.
Publicado: (2022)

Chronic hyperglycaemia increases the vulnerability of the hippocampus to oxidative damage induced during post-hypoglycaemic hyperglycaemia in a mouse model of chemically induced type 1 diabetes
por: McNeilly, Alison D., et al.
Publicado: (2023)

Olfactory bulb acetylcholine release dishabituates odor responses and reinstates odor investigation
por: Ogg, M. Cameron, et al.
Publicado: (2018)

An Estimate of Lifetime Cognitive Change and Its Relationship with Diabetes Health in Older Adults with Type 1 Diabetes: Preliminary Results
por: Johnston, Harriet, et al.
Publicado: (2010)

Advances and Emerging Therapies in the Treatment of Non-alcoholic Steatohepatitis
por: Brennan, Paul N, et al.
Publicado: (2022)

Producing a preference‐based quality of LIFE measure to quantify the impact of HYPOGLYCAEMIA on people living with diabetes: A mixed‐methods research protocol
por: Carlton, Jill, et al.
Publicado: (2022)

Does dapagliflozin regress left ventricular hypertrophy in patients with type 2 diabetes? A prospective, double-blind, randomised, placebo-controlled study
por: Brown, Alexander J.M., et al.
Publicado: (2017)

A taste of Jordan algebras
por: McCrimmon, Kevin
Publicado: (2004)

The fickle Mutation of a Cytoplasmic Tyrosine Kinase Effects Sensitization but not Dishabituation in Drosophila Melanogaster
por: Asztalos, Zoltan, et al.
Publicado: (2007)

Investigating the day-to-day impact of hypoglycaemia in adults with type 1 or type 2 diabetes: design and validation protocol of the Hypo-METRICS application
por: Søholm, Uffe, et al.
Publicado: (2022)

Metformin increases the uptake of glucose into the gut from the circulation in high-fat diet-fed male mice, which is enhanced by a reduction in whole-body Slc2a2 expression
por: Morrice, Nicola, et al.
Publicado: (2023)

Evaluation of Hypoglycaemia with Non-Invasive Sensors in People with Type 1 Diabetes and Impaired Awareness of Hypoglycaemia
por: Elvebakk, Ole, et al.
Publicado: (2018)

Changes in attitudes to awareness of hypoglycaemia during a hypoglycaemia awareness restoration programme are associated with avoidance of further severe hypoglycaemia episodes within 24 months: the A2A in HypoCOMPaSS study
por: Sepúlveda, Eduardo, et al.
Publicado: (2022)

Sun Tzu y el arte de los negocios : seis estrategias fundamentales para el hombre de negocios
por: McNeilly, Mark
Publicado: (1999)

The impact of hypoglycaemia awareness status on regional brain responses to acute hypoglycaemia in men with type 1 diabetes
por: Dunn, Joel T., et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_slc7nmepudb2555lvnos2102s3