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The Virulence of Escherichia coli O157:H7 Isolates in Mice Depends on Shiga Toxin Type 2a (Stx2a)-Induction and High Levels of Stx2a in Stool

In this study we compared nine Shiga toxin (Stx)-producing Escherichia coli O157:H7 patient isolates for Stx levels, stx-phage insertion site(s), and pathogenicity in a streptomycin (Str)-treated mouse model. The strains encoded stx(2a), stx(1a) and stx(2a), or stx(2a) and stx(2c). All of the strain...

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Detalles Bibliográficos
Autores principales:	Hauser, Jocelyn R., Atitkar, Rama R., Petro, Courtney D., Lindsey, Rebecca L., Strockbine, Nancy, O'Brien, Alison D., Melton-Celsa, Angela R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Cellular and Infection Microbiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7054288/ https://www.ncbi.nlm.nih.gov/pubmed/32175286 http://dx.doi.org/10.3389/fcimb.2020.00062

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