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HIF1 driven transcriptional activity regulates steroidogenesis and proliferation of bovine granulosa cells

Hypoxia-inducible factor 1 (HIF1) is a heterodimeric transcription factor, consisting of a constitutively expressed β-subunit (HIF1B) and a regulated α-subunit (HIF1A). In the present study, we analyzed the HIF1 driven transcriptional activity in bovine granulosa cells (GC). Treatment of GC with FSH...

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Detalles Bibliográficos
Autores principales: Baddela, Vijay Simha, Sharma, Arpna, Michaelis, Marten, Vanselow, Jens
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7054295/
https://www.ncbi.nlm.nih.gov/pubmed/32127571
http://dx.doi.org/10.1038/s41598-020-60935-1

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