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CTLA-4 blockade boosts the expansion of tumor-reactive CD8(+) tumor-infiltrating lymphocytes in ovarian cancer
Adoptive cell therapy (ACT) with autologous tumor-infiltrating lymphocytes (TILs) can induce durable complete tumor regression in patients with advanced melanoma. Efforts are currently underway to expand this treatment modality to other cancer types. In the microenvironment of ovarian cancer, the en...
Autores principales: | Friese, Christina, Harbst, Katja, Borch, Troels Holz, Westergaard, Marie Christine Wulff, Pedersen, Magnus, Kverneland, Anders, Jönsson, Göran, Donia, Marco, Svane, Inge Marie, Met, Özcan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7054305/ https://www.ncbi.nlm.nih.gov/pubmed/32127601 http://dx.doi.org/10.1038/s41598-020-60738-4 |
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