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PD-L1 and MRN synergy in platinum-based chemoresistance of head and neck squamous cell carcinoma

BACKGROUND: We have been investigating the molecular mechanisms of cisplatin-induced chemoresistance in head and neck squamous cell carcinoma (HNSCC). Based on our previous findings, the present study investigates how the Mre11, Rad50, and NBS1 (MRN) DNA repair complex interacts at the molecular lev...

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Detalles Bibliográficos
Autores principales:	Shen, Bin, Huang, Dongyan, Ramsey, Andrew J., Ig-Izevbekhai, Kevin, Zhang, Kevin, Lajud, Shayanne A., O’Malley, Bert W., Li, Daqing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7054324/ https://www.ncbi.nlm.nih.gov/pubmed/31853007 http://dx.doi.org/10.1038/s41416-019-0697-x

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