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Microarray analyses reveal strain-specific antibody responses to Plasmodium falciparum apical membrane antigen 1 variants following natural infection and vaccination
Vaccines based on Plasmodium falciparum apical membrane antigen 1 (AMA1) have failed due to extensive polymorphism in AMA1. To assess the strain-specificity of antibody responses to malaria infection and AMA1 vaccination, we designed protein and peptide microarrays representing hundreds of unique AM...
Autores principales: | Bailey, Jason A., Berry, Andrea A., Travassos, Mark A., Ouattara, Amed, Boudova, Sarah, Dotsey, Emmanuel Y., Pike, Andrew, Jacob, Christopher G., Adams, Matthew, Tan, John C., Bannen, Ryan M., Patel, Jigar J., Pablo, Jozelyn, Nakajima, Rie, Jasinskas, Algis, Dutta, Sheetij, Takala-Harrison, Shannon, Lyke, Kirsten E., Laurens, Matthew B., Niangaly, Amadou, Coulibaly, Drissa, Kouriba, Bourema, Doumbo, Ogobara K., Thera, Mahamadou A., Felgner, Philip L., Plowe, Christopher V. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7054363/ https://www.ncbi.nlm.nih.gov/pubmed/32127565 http://dx.doi.org/10.1038/s41598-020-60551-z |
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